| Sequence 1: | NP_001137782.1 | Gene: | Shaw / 33599 | FlyBaseID: | FBgn0003386 | Length: | 619 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002225.2 | Gene: | KCNA5 / 3741 | HGNCID: | 6224 | Length: | 613 | Species: | Homo sapiens |
| Alignment Length: | 516 | Identity: | 185/516 - (35%) |
|---|---|---|---|
| Similarity: | 267/516 - (51%) | Gaps: | 81/516 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 26 RVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRT-GKL 89
Fly 90 HYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKF 154
Fly 155 GFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPD------ 213
Fly 214 -MRVPIVRNITVKTANGSNGWFLDKTQTNAHIA----------FFYIECVCNAWFTFEILVRFIS 267
Fly 268 SPNKWEFIKSSVNIIDYIATLSFYIDLVLQ------------RFASHLENADILEFFSIIRIMRL 320
Fly 321 FKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWW 385
Fly 386 ALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRR 450
Fly 451 VLPVEQPRQPRLPGAPGGV---------SGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDLV 502 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Shaw | NP_001137782.1 | BTB | 27..125 | CDD:197585 | 34/98 (35%) |
| BTB_2 | 27..117 | CDD:280393 | 34/90 (38%) | ||
| Ion_trans | 244..439 | CDD:278921 | 101/216 (47%) | ||
| Ion_trans_2 | 355..429 | CDD:285168 | 46/73 (63%) | ||
| KCNA5 | NP_002225.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..108 | ||
| 2 X 11 AA tandem repeat of D-[SP]-G-V-R-P-L-P-P-L-P | 61..82 | ||||
| BTB_2 | 122..213 | CDD:308049 | 34/98 (35%) | ||
| Ion_trans | 249..526 | CDD:306908 | 121/279 (43%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 282..304 | 6/21 (29%) | |||
| S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 | 418..431 | 6/12 (50%) | |||
| Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 | 480..485 | 4/4 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 532..559 | 10/30 (33%) | |||
| PDZ-binding. /evidence=ECO:0000250 | 611..613 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X19 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||