Protein Alignment Shaw and KCNQ

DIOPT Version :9

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_788300.3
• Gene: KCNQ / 36071
• FlyBaseID: FBgn0033494
• Length: 993
• Species: Drosophila melanogaster
• Alignment Length: 414
• Identity: 93/414 - (22%)
• Similarity: 162/414 - (39%)
• Gaps: 99/414 - (23%)

  Fly   144 KPSEEELARK----FGFEEDYYKGTIS--WWQEMKPRIWSLFDEPYSSNAA-KTIGVVSVFFICI 201
            :|:.|.:.:.    .|...:|.:||..  .::.::.|:::..:.|...:|. ..:.|..:.|.|:
  Fly    24 RPNSERILQPRMSLLGKPLNYNRGTRRDVRYRRLQSRLYNFLERPRGLHAIFYHVMVFLMVFTCL 88

  Fly   202 SILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFI 266
            ::..|.               |:|           :.:.:|....|.:|.:...|||.|...|..
  Fly    89 ALSVFS---------------TIK-----------EYEEDAVYILFRMEILVVIWFTMEFGARLW 127

  Fly   267 SSP---------NKWEFIKSSVNIIDYIATLSFYIDLVL----QRFASHLENADILEFFSIIRIM 318
            ||.         .:.:|:|....|||.:..|:..:.|.:    |.||:.....  |.||.|:|::
  Fly   128 SSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRG--LRFFQILRMV 190

  Fly   319 RLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGL 383
            |   :.|.....|:|.....|..:||...::...||::..:.|||..|:   :.::.|::....|
  Fly   191 R---MDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEK---DVNDKFSNFAQAL 249

  Fly   384 WWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKR 448
            ||.::|:.|||||||.|.|:.|..:.:.|||.|:...|||..::.|.||:.....|.:..:.::|
  Fly   250 WWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRR 314

  Fly   449 RRVLPVEQP-------------------RQPRLPGAPGGVSGCG--------------------- 473
            :....:.|.                   .:..||..|...:...
  Fly   315 QPAATLIQAVWRCYAADEHSVSVATWNIHRVALPSPPASRASSSFKHNTSFVARLPTIRRHKSQT 379

  Fly   474 --TPGSGPHSG---PMGSGGTGPR 492
              |||.|...|   |.||.....|
  Fly   380 IQTPGGGDGGGVSKPPGSSRASTR 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585
		BTB_2	27..117	CDD:280393
		Ion_trans	244..439	CDD:278921	62/207 (30%)
		Ion_trans_2	355..429	CDD:285168	26/73 (36%)
KCNQ	NP_788300.3	Ion_trans	100..305	CDD:278921	63/212 (30%)
		Ion_trans_2	221..295	CDD:285168	28/76 (37%)
		KCNQ_channel	<619..719	CDD:281513

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910