DRSC/TRiP Functional Genomics Resources

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Protein Alignment Shaw and Kcng4

DIOPT Version :9

Sequence 1:NP_001137782.1 Gene:Shaw / 33599 FlyBaseID:FBgn0003386 Length:619 Species:Drosophila melanogaster
Sequence 2:NP_001100905.1 Gene:Kcng4 / 307900 RGDID:1308553 Length:506 Species:Rattus norvegicus


Alignment Length:464 Identity:138/464 - (29%)
Similarity:219/464 - (47%) Gaps:59/464 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 YAHAAMNLINMDSE-----NRVVLNVGGIRHETYKATLKKIPATRLSRL---------TEALANY 61
            |...|..:..:|:.     ..:::||||.|:....:||...|.:|||||         |:...:|
  Rat    39 YYRRARKVSTLDASPEANLKEILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSYEEITQLCDDY 103

  Fly    62 DPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHR 126
            |....|:||||:|..|..::::...|||....::|...|.|||.:||::...:|.||        
  Rat   104 DENSQEFFFDRNPSAFGVIVSFLAAGKLVLLREMCALSFREELSYWGIEEANLERCC-------- 160

  Fly   127 DTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTI 191
                ...:|.:|:...|...||...|:...:..:.:...|.|.....::..:.::|.|....|..
  Rat   161 ----LRKLLKKLEEAAELRREEAAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQSGLPGKVF 221

  Fly   192 GVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAW 256
            ..:||.|:..:.:|.|:.|.||.|           |....|....|.     ...|.:|.:|.||
  Rat   222 ACLSVLFVATTAVSLCVSTMPDFR-----------AEEDKGECARKC-----YYIFVVETICVAW 270

  Fly   257 FTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQ----------RFASHLENAD-ILE 310
            |:.|..:||:.:|||.:|.:..:|:||.:|...:|:.|.:.          ..:|:||... :|.
  Rat   271 FSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDESPEAGERPSGSSYLEKVGLVLR 335

  Fly   311 FFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHND 375
            ....:||:.:.:|.|||.||:.|..|.|..|:|..||:.||.:.:.:|:.|||.||. :.....:
  Rat   336 VLRALRILYVMRLARHSLGLQTLGLTVRRCAREFGLLLLFLGVAVTLFSPLVYVAEN-ESGRVLE 399

  Fly   376 FNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYY----- 435
            |.|||...|||:::|||||||||.|::..|..|.....|:|:|.:|.|...|...|:..|     
  Rat   400 FTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKR 464

  Fly   436 SHTQARAKL 444
            ...|.:|:|
  Rat   465 EQEQVQARL 473

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ShawNP_001137782.1 BTB 27..125 CDD:197585 36/106 (34%)
BTB_2 27..117 CDD:280393 34/98 (35%)
Ion_trans 244..439 CDD:278921 73/210 (35%)
Ion_trans_2 355..429 CDD:285168 31/73 (42%)
Kcng4NP_001100905.1 BTB 60..167 CDD:197585 37/118 (31%)
BTB_2 60..159 CDD:280393 34/98 (35%)
Ion_trans 260..463 CDD:278921 73/203 (36%)
Ion_trans_2 397..457 CDD:285168 26/59 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2126
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X19
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.810

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