Protein Alignment Shaw and KCNG2

DIOPT Version :9

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_016881193.1
• Gene: KCNG2 / 26251
• HGNCID: 6249
• Length: 509
• Species: Homo sapiens
• Alignment Length: 439
• Identity: 149/439 - (33%)
• Similarity: 222/439 - (50%)
• Gaps: 50/439 - (11%)

  Fly    27 VVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPIL----------NEYFFDRHPGVFAQVL 81
            |::||||.|.....|.|.:.|..||.|| .|...:|.:|          :|:||||.|..|..::
Human    62 VIINVGGCRVRLAWAALARCPLARLERL-RACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIV 125

  Fly    82 NYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPS 146
            ...|.|||......|...|.:||.:||:|..::|.|| :...:.|:.:...|...    .||:.:
Human   126 ALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC-LRRLRRREEEAAEARAG----PTERGA 185

  Fly   147 EEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTH 211
            :...||..|     .:|.:   |..:.|:..:.|.|:|..|.|....|||.|:.::.:..||.|.
Human   186 QGSPARALG-----PRGRL---QRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTM 242

  Fly   212 PDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIK 276
            ||:|           |....|....|.:     :.|.:|.||.|||:||.|:|.:.:.:|..|::
Human   243 PDIR-----------AEEERGECSPKCR-----SLFVLETVCVAWFSFEFLLRSLQAESKCAFLR 291

  Fly   277 SSVNIIDYIATLSFYIDLVLQRFASH-----LENAD-ILEFFSIIRIMRLFKLTRHSSGLKILIQ 335
            :.:||||.:|.|.||:.|:|...|..     ||.|. :|.....:|::.:.:|.|||.||:.|..
Human   292 APLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGL 356

  Fly   336 TFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAP 400
            |.|..|:|..||:.||.:.:.:||.||:.||| :.....||:|:|...|||:::|||||||||.|
Human   357 TMRRCAREFGLLLLFLCVAMALFAPLVHLAER-ELGARRDFSSVPASYWWAVISMTTVGYGDMVP 420

  Fly   401 KTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYS---HTQARAKLPK 446
            ::..|..|.....|:|:|.:|.||..|...|:..||   ..|.||..|:
Human   421 RSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPE 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	37/107 (35%)
		BTB_2	27..117	CDD:280393	35/99 (35%)
		Ion_trans	244..439	CDD:278921	80/203 (39%)
		Ion_trans_2	355..429	CDD:285168	33/73 (45%)
KCNG2	XP_016881193.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820