DRSC/TRiP Functional Genomics Resources

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Protein Alignment Shaw and Kcns3

DIOPT Version :9

Sequence 1:NP_001137782.1 Gene:Shaw / 33599 FlyBaseID:FBgn0003386 Length:619 Species:Drosophila melanogaster
Sequence 2:NP_001162036.1 Gene:Kcns3 / 238076 MGIID:1098804 Length:491 Species:Mus musculus


Alignment Length:432 Identity:136/432 - (31%)
Similarity:225/432 - (52%) Gaps:52/432 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 ENRVVLNVGGIRHETYKATLKKIPATRLSRL---------TEALANYDPILNEYFFDRHPGVFAQ 79
            |..|.|||||.:....::||.:.|.|||.:|         .|...:|.....||:|||:|.:|..
Mouse    14 EELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPFLFRY 78

  Fly    80 VLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDR------L 138
            |||:|.|||||...::|...|.:|:|:||::...::.||...|.:.::...     |:      .
Mouse    79 VLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSSRYQERKEESH-----DKDWDQKSN 138

  Fly   139 DLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISI 203
            |:.|:...||...    ||::..|.....:.:::.:||...:.|....:||.|.:.|:..:..||
Mouse   139 DVSTDSSFEESSL----FEKELEKFDELRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASI 199

  Fly   204 LSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISS 268
            ::.|:.:..:.:             ..:|...|.......||       |.||||.|:.:|.:::
Mouse   200 VAMCVHSMSEFQ-------------NEDGEVDDPVLEGVEIA-------CIAWFTGELAIRLVAA 244

  Fly   269 PNKWEFIKSSVNIIDYIATLSFYIDLVL---QRFASHLEN-ADILEFFSIIRIMRLFKLTRHSSG 329
            |::.:|.|:.:||||:::.:.||..|.:   :..:..:|| ..:::...::||.|:.||.|||.|
Mouse   245 PSQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVG 309

  Fly   330 LKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPH-NDFNSIPLGLWWALVTMTTV 393
            |:.|..|.|.|..|:.||:.||.:||.||:.|:|..|:   :.| :...|||:..|||.::||||
Mouse   310 LRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEK---DEHKSSLTSIPICWWWATISMTTV 371

  Fly   394 GYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYY 435
            ||||..|.|..|..:.:.|.:.|:|.:|||:.:|.:.|:.||
Mouse   372 GYGDTHPVTLAGKIIASTCIICGILVVALPITIIFNKFSKYY 413

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ShawNP_001137782.1 BTB 27..125 CDD:197585 40/106 (38%)
BTB_2 27..117 CDD:280393 37/98 (38%)
Ion_trans 244..439 CDD:278921 75/197 (38%)
Ion_trans_2 355..429 CDD:285168 31/74 (42%)
Kcns3NP_001162036.1 BTB_POZ_KCNS3 15..122 CDD:349735 39/106 (37%)
Ion_trans 184..417 CDD:366146 84/253 (33%)
Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 370..375 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2126
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D818306at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X19
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.820

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