DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and KCTD2

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_056168.1	Gene:	KCTD2 / 23510	HGNCID:	21294	Length:	263	Species:	Homo sapiens

Alignment Length:	92	Identity:	33/92 - (35%)
Similarity:	42/92 - (45%)	Gaps:	10/92 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 VVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNE-------YFFDRHPGVFAQVLNYY 84
            |.|||||....|.:.||.:.|.:.|.||   ....||.|:.       |..||.|..|..:|||.
Human    74 VRLNVGGTYFVTTRQTLGREPKSFLCRL---CCQEDPELDSDKDETGAYLIDRDPTYFGPILNYL 135

  Fly    85 RTGKLHYPTDVCGPLFEEELEFWGLDS 111
            |.|||....::......||.||:.:.|
Human   136 RHGKLIITKELAEEGVLEEAEFYNIAS 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	33/92 (36%)
		BTB_2	27..117	CDD:280393	33/92 (36%)
		Ion_trans	244..439	CDD:278921
		Ion_trans_2	355..429	CDD:285168
KCTD2	NP_056168.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..69
KCTD2	NP_056168.1	BTB_POZ_KCTD2	72..177	CDD:349697	33/92 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910