DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and twk-7

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_498903.3	Gene:	twk-7 / 192073	WormBaseID:	WBGene00006662	Length:	557	Species:	Caenorhabditis elegans

Alignment Length:	150	Identity:	41/150 - (27%)
Similarity:	62/150 - (41%)	Gaps:	47/150 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 HSSGLKILIQTFRASA-KELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVT 389
            |..|..:.|:..|..| ..|.:|:.:...|.|:.:.|         .|.:.|.|    .:|:.:|
Worm   356 HGMGHDMNIEEKRIPAFLVLAILIVYTAFGGVLMSKL---------EPWSFFTS----FYWSFIT 407

  Fly   390 MTTVGYGDMAPK---------TYI--GMFVGALCA-LAGVLTI---------------ALPV--- 424
            |||||:||:.|:         .||  |:.:..:|. |.||..|               ||.|
Worm   408 MTTVGFGDLMPRRDGYMYIILLYIILGLAITTMCIDLVGVQYIRKIHYFGRKIQDARSALAVVGG 472

  Fly   425 -PVIVSNFAMYYSHTQARAK 443
             .|:||.  :|.:..|.||:
Worm   473 KVVLVSE--LYANLMQKRAR 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585
		BTB_2	27..117	CDD:280393
		Ion_trans	244..439	CDD:278921	38/144 (26%)
		Ion_trans_2	355..429	CDD:285168	27/104 (26%)
twk-7	NP_498903.3	Ion_trans_2	<263..321	CDD:285168
		Ion_trans	<371..>418	CDD:278921	18/59 (31%)
		Ion_trans_2	377..>422	CDD:285168	17/57 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000