DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and kqt-3

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_001254403.1	Gene:	kqt-3 / 191699	WormBaseID:	WBGene00002235	Length:	621	Species:	Caenorhabditis elegans

Alignment Length:	297	Identity:	66/297 - (22%)
Similarity:	122/297 - (41%)	Gaps:	69/297 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 KPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLD 236
            :|..|..|...:|        |..:..||: |||                            .|.
Worm    70 RPTGWKCFLYHFS--------VFLIVLICL-ILS----------------------------VLS 97

  Fly   237 KTQTNAHIA---FFYIECVCNAWFTFEILVR---------FISSPNKWEFIKSSVNIIDYIATLS 289
            ..:.::|.|   .:.:|.|...:|:.|.:||         :|....:.:|::..:.:||.:..:.
Worm    98 TVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVIC 162

  Fly   290 FYIDLVL----QRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFF 350
            ....:..    |.||     |..:.....::|:|:..:.|.....::|........:||...::.
Worm   163 SLFVICFGTEGQVFA-----ASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYI 222

  Fly   351 LVLGIVIFASLVYYAER--IQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCA 413
            ..||::..:..||.||:  |..:....|.|....|||.::||||:||||:.|:|::|..|.:..:
Worm   223 GFLGLIFSSYFVYLAEKDHIGVDGRQAFTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFS 287

  Fly   414 LAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRR 450
            :..:...|||..::.|.||:         |:.:|:|:
Worm   288 IFAISFFALPAGILGSGFAL---------KVQQKQRQ 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585
		BTB_2	27..117	CDD:280393
		Ion_trans	244..439	CDD:278921	51/212 (24%)
		Ion_trans_2	355..429	CDD:285168	25/75 (33%)
kqt-3	NP_001254403.1	Ion_trans	108..313	CDD:278921	51/218 (23%)
		Ion_trans_2	224..303	CDD:285168	27/78 (35%)
		KCNQ_channel	<460..560	CDD:281513
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910