DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and sdz-35

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_494473.2	Gene:	sdz-35 / 191123	WormBaseID:	WBGene00022570	Length:	225	Species:	Caenorhabditis elegans

Alignment Length:	168	Identity:	46/168 - (27%)
Similarity:	66/168 - (39%)	Gaps:	37/168 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGK 88
            :.::.||:||...||.|:||.|......:.|...:.......|..|.||.|..|.::|||.|.|
Worm     5 DEKIRLNIGGTIFETSKSTLTKFDGFFKTLLETEIPIQKDDSNCIFIDRSPRHFEKILNYLRDG- 68

  Fly    89 LHYPTDVCGPLFEE----------ELEFWGLDSNQVEPC----CWM-TYTQHRDTQETLA----- 133
                .||  .|..|          |.:|: |....:|.|    |.| |:..:.|..:.:|
Worm    69 ----ADV--DLLPESEKEVREILKEAQFY-LKEGLMELCKRSTCKMRTFDSYHDLLKLIAEAGKP 126

  Fly   134 --VLDRLDLD---TEKPS----EEELARKFGFEEDYYK 162
              |:..|..|   ...||    .:.|.:..|..|.|:|
Worm   127 VLVIFYLVKDNRIVHIPSNFKIRDFLEKHHGMLEIYFK 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	34/112 (30%)
		BTB_2	27..117	CDD:280393	30/99 (30%)
		Ion_trans	244..439	CDD:278921
		Ion_trans_2	355..429	CDD:285168
sdz-35	NP_494473.2	BTB_2	8..100	CDD:366986	30/99 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910