DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and kqt-2

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_509392.3	Gene:	kqt-2 / 181078	WormBaseID:	WBGene00002234	Length:	695	Species:	Caenorhabditis elegans

Alignment Length:	312	Identity:	72/312 - (23%)
Similarity:	130/312 - (41%)	Gaps:	78/312 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 LDLDTEKPSEEELARKFGFEEDYYKGTISWWQE-------MKPRIWSLFDEPYSSNAAKTIGVVS 195
            |.:|..:.||.|::     :....:.||:...:       ::.::::..::|.::.:|.     .
Worm    42 LTIDDAEDSETEVS-----DNIRRRSTINLGNQRQRNLRRIRLKVYNFLEKPLNAASAP-----Y 96

  Fly   196 VFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFE 260
            .|||      |.|         ::.||.:..|...|    |.|.:..|   |::|.....:|..|
Worm    97 HFFI------FGL---------VIANIILGAATNDN----DSTVSKIH---FFLEIFMIVFFILE 139

  Fly   261 ILVRF--ISSPNKWE-------FIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIR 316
            ..||.  :.:..|:.       ::..:|.:||.:...:..:.||   |..|..:...|:....|:
Worm   140 FAVRLWSVRADAKYRTKYGRLYYLFHTVTLIDILIIPATILLLV---FKGHDVDGSTLDTLRFIQ 201

  Fly   317 IMRLFKLTRHSSGLKILIQTFRASAKELTLLVFF-LVLGIVIFASLVY----YAERIQPNPHN-- 374
            |:|||.:.|..:..|:|.:.......:|....:. ||:|:.: |::||    .|:.||.|.:.
Worm   202 ILRLFHVDRQMATWKLLRKMIILGKWQLMATYYITLVVGLSL-ATIVYSTEALAQGIQDNGYGLI 265

  Fly   375 -------DFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGAL-----CAL 414
                   .|.::....|:..||:.||||||:.|       ||||     |.|
Worm   266 VPEGTNATFPTMAHSWWFTAVTVMTVGYGDIYP-------VGALTKFLVCVL 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585
		BTB_2	27..117	CDD:280393
		Ion_trans	244..439	CDD:278921	51/199 (26%)
		Ion_trans_2	355..429	CDD:285168	24/78 (31%)
kqt-2	NP_509392.3	Ion_trans	96..318	CDD:366146	63/248 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810