DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and twk-9

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_001294002.1	Gene:	twk-9 / 177803	WormBaseID:	WBGene00006664	Length:	568	Species:	Caenorhabditis elegans

Alignment Length:	158	Identity:	38/158 - (24%)
Similarity:	61/158 - (38%)	Gaps:	41/158 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   378 SIPLGLWWALVTMTTVGYGDMAPKTYIG----MFVGALCALAGVLTIALPVPVIVSNFAMYYSH- 437
            ||...:.:|...:||:|||.:||:|:.|    :|.|.:.....:||||        :..|:.:.
Worm   162 SIGNSVIFAFTVITTIGYGHVAPETFEGRLFLIFYGVIGVPFTLLTIA--------DLGMFLTRF 218

  Fly   438 -----TQAR------AKLPKKRRRVLPVEQPRQPRLPGAP-GGVSGCG------------TPGSG 478
                 |.||      .||.:|.::.....|...|.:|.:. ..|...|            .||.|
Worm   219 LKNLLTMARRFAHYLVKLYQKAKKQRNKSQKTSPVMPDSERSEVWNTGKEMKEMSMRTAREPGEG 283

  Fly   479 PHSGPMGSGGTGPRRMNNKTKDLVSPKS 506
            .....:.:|..    .|.|.:|...|::
Worm   284 DEIEVIENGND----ENGKEEDEEEPEN 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585
		BTB_2	27..117	CDD:280393
		Ion_trans	244..439	CDD:278921	19/70 (27%)
		Ion_trans_2	355..429	CDD:285168	18/54 (33%)
twk-9	NP_001294002.1	Ion_trans_2	<159..217	CDD:285168	19/62 (31%)
twk-9	NP_001294002.1	Ion_trans_2	321..397	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000