DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and F18A11.5

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_001254362.1	Gene:	F18A11.5 / 174943	WormBaseID:	WBGene00008932	Length:	231	Species:	Caenorhabditis elegans

Alignment Length:	189	Identity:	50/189 - (26%)
Similarity:	76/189 - (40%)	Gaps:	57/189 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RVVLNVGGIRHETYKATLKKIPATRLS-RLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKL 89
            ||:|||||.:.||..|||.::..|.|: .:::.....|    |.|.||.|..|.:||||.|.|.
Worm    21 RVLLNVGGKKFETTVATLTRVSDTVLAVMVSDRWKTGD----EIFIDRDPKHFGKVLNYLRDGD- 80

  Fly    90 HY----PTDVCGPLFEEELEF----------------------WGLDSNQVEPCCWMTYTQHR-- 126
            |:    .|:.|..| :.|..|                      |..|:.::   .|..:.::.
Worm    81 HFVAPSDTEACDEL-KREAHFYNMPFLAEMCMPMNVDVADVVQWKRDAIEI---YWRPFVRYMVD 141

  Fly   127 DTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSS 185
            |:.....:.||        :...|||....||         :|:  |:...|||..|::
Worm   142 DSLSLPFIYDR--------NNHTLARCIACEE---------FQD--PKCSYLFDINYTA 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	35/124 (28%)
		BTB_2	27..117	CDD:280393	34/116 (29%)
		Ion_trans	244..439	CDD:278921
		Ion_trans_2	355..429	CDD:285168
F18A11.5	NP_001254362.1	BTB_POZ	22..102	CDD:365784	32/85 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910