DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and C40A11.4

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_494195.3	Gene:	C40A11.4 / 173571	WormBaseID:	WBGene00016547	Length:	228	Species:	Caenorhabditis elegans

Alignment Length:	196	Identity:	45/196 - (22%)
Similarity:	69/196 - (35%)	Gaps:	59/196 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 MDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFF-DRHPGVFAQVLNYY 84
            |...:.|.||:||...:|.:.||     :..:.|.:.:...|....|..| .|.|..|..:|||.
Worm     1 MPVSSTVKLNIGGEAFKTSRTTL-----SHFNGLFKTMLEKDTATTELSFPHRSPKHFDLILNYM 60

  Fly    85 RTGKLHYP------TDVCGPLFEEELEFWGLDSNQVEPCC---WMTYTQHRDTQETLAVLDRLDL 140
            |.|.:..|      .:|     .||.||:.|  |::...|   |:                   :
Worm    61 RDGDVLLPRNNKELAEV-----REEAEFYQL--NELARQCDSIWI-------------------V 99

  Fly   141 DTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRI--------WSLFDEPYSSNAAKTIGVVSVF 197
            ...|...|.|.|..|.::|.   .:.|:...|..:        :..|.|.||..       :.|:
Worm   100 QYNKGPREMLRRIAGSKKDI---LVVWYSTHKDELINCPEDFSFPYFYEQYSDK-------IDVY 154

  Fly   198 F 198
            |
Worm   155 F 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	30/107 (28%)
		BTB_2	27..117	CDD:280393	28/96 (29%)
		Ion_trans	244..439	CDD:278921
		Ion_trans_2	355..429	CDD:285168
C40A11.4	NP_494195.3	BTB	7..90	CDD:383002	28/94 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910