Protein Alignment Shaw and KCNG3

DIOPT Version :9

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_579875.1
• Gene: KCNG3 / 170850
• HGNCID: 18306
• Length: 436
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 152/448 - (33%)
• Similarity: 225/448 - (50%)
• Gaps: 67/448 - (14%)

  Fly    27 VVLNVGGIRHETYKATLKKIPATRLSRL---------TEALANYDPILNEYFFDRHPGVFAQVLN 82
            |||||||.|:...:..||..|..|:|||         .|...:||...||||||||...|..:|.
Human    11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGFILL 75

  Fly    83 YYR-TGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWM--------TYTQHRDTQETLAVLDRL 138
            |.| .|||.:...:|...|..|:.:|||:...:|.||..        |||.:  :.:...||.|
Human    76 YVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFY--SADEPGVLGR- 137

  Fly   139 DLDTEKPSEEELA--RKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICI 201
              |..:|...|.|  |:             |.:.|:    ..|:||.||.||:.:..|||.|:.:
Human   138 --DEARPGGAEAAPSRR-------------WLERMR----RTFEEPTSSLAAQILASVSVVFVIV 183

  Fly   202 SILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNA---HIAFFYIECVCNAWFTFEILV 263
            |::..|..|.||.|          .|...|....|:::.:|   ......||.:|..|||.|.:|
Human   184 SMVVLCASTLPDWR----------NAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAECIV 238

  Fly   264 RFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFA---SHLENADILEFFSIIRIMRLF---K 322
            |||.|.||.||:|..:||||.:|...:||.:::..|.   |.|:.|.:.  ..::|:||:|   |
Human   239 RFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVT--LRVLRMMRIFWVIK 301

  Fly   323 LTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAER---IQPNPHNDFNSIPLGLW 384
            |.||..||:.|..|.:...:|:.:|:.|:.:.:.||::|....|.   ::.: :.||.|||...|
Human   302 LARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETS-NKDFTSIPAACW 365

  Fly   385 WALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARA 442
            |.:::|||||||||.|.|..|..:|.:|.::|::.:|||:..|..:|...|...:.|:
Human   366 WVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRS 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	45/115 (39%)
		BTB_2	27..117	CDD:280393	40/99 (40%)
		Ion_trans	244..439	CDD:278921	75/203 (37%)
		Ion_trans_2	355..429	CDD:285168	30/76 (39%)
KCNG3	NP_579875.1	BTB_POZ_KCNG3	11..122	CDD:349729	42/110 (38%)
		Ion_trans	219..420	CDD:395416	75/203 (37%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	373..378		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820