Protein Alignment Shaw and Kcnq1

DIOPT Version :9

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_006508551.2
• Gene: Kcnq1 / 16535
• MGIID: 108083
• Length: 688
• Species: Mus musculus
• Alignment Length: 383
• Identity: 81/383 - (21%)
• Similarity: 149/383 - (38%)
• Gaps: 66/383 - (17%)

  Fly   247 FYIECVCNAWFTFEILVRFISSPNK------W---EFIKSSVNIIDYIATLSFYIDLVL----QR 298
            |::|.|...:|..|.:||..|:..:      |   .|.:..::|||.|..::..:.|.:    |.
Mouse   176 FWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQV 240

  Fly   299 FASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVY 363
            ||:     ..:.....::|:|:..:.|.....::|........:||...::...||::..:..||
Mouse   241 FAT-----SAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVY 300

  Fly   364 YAER--IQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPV 426
            .||:  :..:...:|.|....|||.:||:||:||||..|:|::|..:.:..::..:...|||..:
Mouse   301 LAEKDAVNESGRIEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGI 365

  Fly   427 IVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVSGCGT--PGSGPHSGPMGSGGT 489
            :.|.||:         |:.:|:|     ::....::|.|...:.....  ....|.|........
Mouse   366 LGSGFAL---------KVQQKQR-----QKHFNRQIPAAASLIQTAWRCYAAENPDSATWKIYVR 416

  Fly   490 GPRRMNNKTKDLVSPKSVAQLFAGPLGASIVAMSPRTMLDLNPALAMGKPTFQPRIPTPLAATPP 554
            .|.|.:........||.           |::....:..||.:..::.|:..|.    .|.....|
Mouse   417 KPARSHTLLSPSPKPKK-----------SVMVKKKKFKLDKDNGMSPGEKMFN----VPHITYDP 466

  Fly   555 PPVSSAGGMTASGIGTTSATGATSAPQPATPLPSIAVST-----TASVGKDLGISTTT 607
            |........:..|..::.....|          .:.|||     |.|..:||.:...|
Mouse   467 PEDRRPDHFSIDGYDSSVRKSPT----------LLEVSTPHFLRTNSFAEDLDLEGET 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585
		BTB_2	27..117	CDD:280393
		Ion_trans	244..439	CDD:278921	52/206 (25%)
		Ion_trans_2	355..429	CDD:285168	23/75 (31%)
Kcnq1	XP_006508551.2	Ion_trans	149..378	CDD:366146	53/215 (25%)
		KCNQ_channel	<530..636	CDD:367540

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810