DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and Kcnk7

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_034739.2	Gene:	Kcnk7 / 16530	MGIID:	1341841	Length:	343	Species:	Mus musculus

Alignment Length:	251	Identity:	48/251 - (19%)
Similarity:	77/251 - (30%)	Gaps:	115/251 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly   344 LTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPK------- 401
            |...||.|:..:|::.        :|.:     .|:...:::...:::|:|.||:.|.
Mouse   177 LVACVFMLLPALVLWG--------VQGD-----CSLLEAIYFCFGSLSTIGLGDLLPAHGRGLHP 228

  Fly   402 --TYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPG 464
              .::|.|     ||.|.|.:.|        .||..: .:..::||:.|..|
Mouse   229 AIYHLGQF-----ALLGYLLLGL--------LAMLLA-VETFSELPQVRAMV------------- 266

  Fly   465 APGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDLVSPKSVAQLFAGPLGASIVAMSPRTMLD 529
                          ...||.||       ..::.:|            |.||...:|:|
Mouse   267 --------------KFFGPSGS-------RTDEDQD------------GILGQDELALS------ 292

  Fly   530 LNPALAMGKPTFQPRIPTPLAATPPPPVSSAGGMTASGIGTTSATGATSAPQPATP 585
                      |..|..|. |..|.|..||.                ..:.||||.|
Mouse   293 ----------TVLPDAPV-LGPTTPASVSE----------------HQNRPQPADP 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585
		BTB_2	27..117	CDD:280393
		Ion_trans	244..439	CDD:278921	21/103 (20%)
		Ion_trans_2	355..429	CDD:285168	15/82 (18%)
Kcnk7	NP_034739.2	Ion_trans_2	<89..140	CDD:285168
Kcnk7	NP_034739.2	Ion_trans_2	178..>225	CDD:285168	11/59 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000