Protein Alignment Shaw and Kcnc3

DIOPT Version :9

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_446449.2
• Gene: Kcnc3 / 117101
• RGDID: 621358
• Length: 769
• Species: Rattus norvegicus
• Alignment Length: 612
• Identity: 258/612 - (42%)
• Similarity: 336/612 - (54%)
• Gaps: 104/612 - (16%)

  Fly    26 RVVLNVGGIRHETYKATLKKIPATRLSRLTE----ALANYDPILNEYFFDRHPGVFAQVLNYYRT 86
            ::|:||||:|||||::||:.:|.|||:.|||    |..:|||..:|:||||||||||.|||||||
  Rat    91 KIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGTDEFFFDRHPGVFAYVLNYYRT 155

  Fly    87 GKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELA 151
            ||||.|.|||||||||||.|||:|...||.||||||.||||.:|.|...:..|......:....|
  Rat   156 GKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDSSGNANANAGGA 220

  Fly   152 RKFGFEE---------DYYKGTI------------------------SWWQEMKPRIWSLFDEPY 183
            ...|.::         |...|.:                        :||:..:||:|:||::||
  Rat   221 HDAGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPAGGPGGAGGTWWRRWQPRVWALFEDPY 285

  Fly   184 SSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTAN---GSNGWFLDKTQTNAHIA 245
            ||.||:.:...|:|||.|||.:|||:||...  ..:.|.||..|:   |:....:...:......
  Rat   286 SSRAARYVAFASLFFILISITTFCLETHEGF--IHISNKTVTQASPIPGAPPENITNVEVETEPF 348

  Fly   246 FFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILE 310
            ..|:|.||..|||||.|:|....|:|.||:|||:||||.:|.|.||:::.|...:|.... |:|.
  Rat   349 LTYVEGVCVVWFTFEFLMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAK-DVLG 412

  Fly   311 FFSI---IRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNP 372
            |..:   :||:|:||||||..||::|..|.|||..|..||:.||.||::|||:::||||||..:|
  Rat   413 FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADP 477

  Fly   373 -------HNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSN 430
                   |..|.:||:|.|||:|||||:|||||.|||:.||.||||||||||||||:||||||:|
  Rat   478 DDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNN 542

  Fly   431 FAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVSGCGTPGSGPHSGPMGSGGTGPRRMN 495
            |.||||...|:.|||||:.:.:|     :|..||:|........|...||. ..||||..|
  Rat   543 FGMYYSLAMAKQKLPKKKNKHIP-----RPPQPGSPNYCKPDPPPPPPPHP-HHGSGGISP---- 597

  Fly   496 NKTKDLVSPKSVAQLFAGPLGASIVAMSPRTMLDLNPALAMGKPTFQPRIPTPLAATPPPPVSSA 560
               ...::|.|:....||                                     |.||.| .:.
  Rat   598 ---PPPITPPSMGVTVAG-------------------------------------AYPPGP-HTH 621

  Fly   561 GGMTASGIGTTSATGATSAPQPATPLP 587
            .|:...|.|.....|....|.|..|.|
  Rat   622 PGLLRGGAGGLGIMGLPPLPAPGEPCP 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	69/101 (68%)
		BTB_2	27..117	CDD:280393	63/93 (68%)
		Ion_trans	244..439	CDD:278921	113/204 (55%)
		Ion_trans_2	355..429	CDD:285168	52/80 (65%)
Kcnc3	NP_446449.2	BTB	92..194	CDD:197585	69/101 (68%)
		BTB_2	92..186	CDD:280393	63/93 (68%)
		Ion_trans	344..551	CDD:278921	113/207 (55%)
		Ion_trans_2	460..541	CDD:285168	52/80 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	255	1.000	Domainoid score	I1967
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	460	1.000	Inparanoid score	I1505
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D331021at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45048
orthoMCL	1	0.900	-	-		OOG6_102927
Panther	1	1.100	-	-	O	PTHR11537
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.970