Protein Alignment Shaw and kcnk4a

DIOPT Version :10

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_068069404.1
• Gene: kcnk4a / 101885817
• ZFINID: ZDB-GENE-141211-80
• Length: 542
• Species: Danio rerio
• Alignment Length: 318
• Identity: 61/318 - (19%)
• Similarity: 100/318 - (31%)
• Gaps: 131/318 - (41%)

  Fly   338 RASAKELTLL---------------VFFLVLGIVIFASLVYYAERIQPNPHNDFN-----SIPLG 382
            ||.||..||.               ||.:::|.::|.::          |...|.     |:...
Zfish   145 RAVAKVETLFLRKGVKPTSVRIISAVFSILIGCLVFIAV----------PTMVFQEVESWSLLEA 199

  Fly   383 LWWALVTMTTVGYGDMA------------PKTYIGMFVGALCALAGVLTI--------------- 420
            :::.::|:||||:||..            |..::.:..| |...|.:||:
Zfish   200 VYFVVITLTTVGFGDYVAENRRDGTPLYKPLVWLWIVFG-LAYFASILTMIGNWLRVLSKKTRAE 263

  Fly   421 ----------------------ALPVPVIVSNFAMYYSHTQARAKLPKKRRRVL------PVEQP 457
                                  .:|||:.:::          ..:|.::|||..      ....|
Zfish   264 MEELRAHATDWTQNIQNMSMDFRIPVPLDLND----------PFQLQRRRRRKRHHHHHHHHRHP 318

  Fly   458 RQPRLPGAPGGVS--------------GCGTPGSGPHSGPMGSGGTGPRRMNNKTKDLVSPKSVA 508
            | |...|...|:|              |..|....|.|..:...    |.|:.........:..:
Zfish   319 R-PNTTGLTHGISLDADIIRENGHLILGWPTCRYKPASEVLSQS----RSMSRIDGAHYEMRPGS 378

  Fly   509 QLFAGPLGASIVAMSPRTMLDLNPALAMGKPTFQPRIPTPLAATPPPPVSSAGGMTAS 566
            :|..||...||      :.|:|.||...|.          .|.:..|..|.:|..:||
Zfish   379 RLTVGPTSRSI------SRLELKPASRAGS----------RAISRSPSQSESGSFSAS 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB_Shaw-like	24..135	CDD:349723
		Ion_trans	188..439	CDD:459842	29/169 (17%)
		PRK14959	<418..>585	CDD:184923	37/206 (18%)
kcnk4a	XP_068069404.1	Ion_trans_2	<82..137	CDD:462301
		Ion_trans_2	170..254	CDD:462301	20/94 (21%)