DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and kcnk17

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	XP_005158968.1	Gene:	kcnk17 / 101882139	ZFINID:	ZDB-GENE-120113-3	Length:	299	Species:	Danio rerio

Alignment Length:	164	Identity:	41/164 - (25%)
Similarity:	63/164 - (38%)	Gaps:	44/164 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   295 VLQRFASHLENADILEFFSIIRI------------------MRLFKLTRHSSGLKILIQTFRASA 341
            :|..|:..|     .:|.|:.|:                  :..:||    .|..:|.|......
Zfish     1 MLSMFSGRL-----CQFLSVTRLPSILFLGVFYVAYVLVGGLVFWKL----EGWYVLQQIALLKE 56

  Fly   342 KELTLLVFFLVL---GIVIFASLVYYAERIQPNPHNDFNSIPLGLW-------WALVTMTTVGYG 396
            |.|.||..:..|   |:...|.::..|.....:|  |.|....|||       :|...:||:|||
Zfish    57 KRLELLEKYPCLGQNGLSELAQMIKSASLSGLSP--DSNDTADGLWKFTSSSVFAATVVTTIGYG 119

  Fly   397 DMAPKTYIGMFVGALCALAGVLTIALPVPVIVSN 430
            ::.|.|..|.....:.||.|:     |:.|:|.|
Zfish   120 NIVPLTTAGQIFCVMFALFGI-----PLNVVVLN 148

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585
		BTB_2	27..117	CDD:280393
		Ion_trans	244..439	CDD:278921	41/164 (25%)
		Ion_trans_2	355..429	CDD:285168	22/80 (28%)
kcnk17	XP_005158968.1	Ion_trans_2	<100..154	CDD:285168	17/54 (31%)
kcnk17	XP_005158968.1	Ion_trans_2	189..267	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000