DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and LOC100537363

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	XP_009301042.1	Gene:	LOC100537363 / 100537363	-ID:	-	Length:	856	Species:	Danio rerio

Alignment Length:	287	Identity:	70/287 - (24%)
Similarity:	118/287 - (41%)	Gaps:	49/287 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 KPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLD 236
            :||.|:.....|         |..:.|.|:.:..|.               |:|
Zfish    87 RPRGWAFIYHAY---------VFLLVFSCLVLSVFS---------------TIK----------- 116

  Fly   237 KTQTNAHIAFFYIECVCNAWFTFEILVRFISS---------PNKWEFIKSSVNIIDYIATLSFYI 292
            :.:.::..|.:.:|.|....|..|.:||..|:         ..:.:|.:....:|| |..|...|
Zfish   117 EYEKSSEDALYILEIVTIVVFGVEYIVRIWSAGCCCRYRGWRGRLKFARKPFCVID-IMVLIASI 180

  Fly   293 DLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVI 357
            .::......::.....:.....::|:|:.::.|.....|:|.....|.:|||....:...|.:::
Zfish   181 SVLAAGTQGNVFATSAIRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLCLIL 245

  Fly   358 FASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIAL 422
            .:.|||.||:   ..:..|.:....|||.|:|:||:||||..|.|:.|..:.|...|.||...||
Zfish   246 ASFLVYLAEK---EDNEMFETYADALWWGLITLTTIGYGDKYPITWNGRLLAATFTLIGVSFFAL 307

  Fly   423 PVPVIVSNFAMYYSHTQARAKLPKKRR 449
            |..::.|.||:.... |.|.|..:|||
Zfish   308 PAGILGSGFALKVQE-QHRQKHFEKRR 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585
		BTB_2	27..117	CDD:280393
		Ion_trans	244..439	CDD:278921	54/203 (27%)
		Ion_trans_2	355..429	CDD:285168	27/73 (37%)
LOC100537363	XP_009301042.1	Ion_trans	119..324	CDD:278921	54/209 (26%)
		Ion_trans_2	240..314	CDD:285168	28/76 (37%)
		KCNQ_channel	444..646	CDD:281513
		KCNQ2_u3	655..735	CDD:293248
		KCNQC3-Ank-G_bd	766..853	CDD:288784
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810