Protein Alignment Shaw and LOC100497714

DIOPT Version :9

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_012822914.1
• Gene: LOC100497714 / 100497714
• -ID: -
• Length: 621
• Species: Xenopus tropicalis
• Alignment Length: 642
• Identity: 275/642 - (42%)
• Similarity: 360/642 - (56%)
• Gaps: 125/642 - (19%)

  Fly    20 NMDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTE--ALAN--YDPILNEYFFDRHPGVFAQV 80
            |.||: ::|:||||||||||::|||.:|.||||.|||  |.:|  |||..:|:||||||.|||.|
 Frog    32 NEDSD-KIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYV 95

  Fly    81 LNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKP 145
            ||||||||||.|.||||||:||||.|||:|...||.||||.|.||||.:|.|.     ..:|.:|
 Frog    96 LNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEACCWMNYRQHRDAEEALD-----SFETPEP 155

  Fly   146 SEEEL---ARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFC 207
            :|||.   .::...:||..|  :..|:.::|::|:||::||||.||:.|...|:|||.|||.:||
 Frog   156 TEEEEDGDLKRLCLQEDGRK--LGRWKRLQPKVWALFEDPYSSKAARYIAFASLFFILISITTFC 218

  Fly   208 LKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIA----FFYIECVCNAWFTFEILVRFISS 268
            |:||....  .|.|.|.....|:    :.:|:|...:.    ..|:|.:|..|||||.|:|.|..
 Frog   219 LETHEAFN--DVNNKTEVFTQGN----ITRTETILEMETEPFLTYVEGICVIWFTFEFLIRVIFC 277

  Fly   269 PNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSI---IRIMRLFKLTRHSSGL 330
            |:|.||||||:||||::|.|.||:::.|...:|.... |:|.|..:   :||:|:||||||..||
 Frog   278 PDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSKAAK-DVLGFLRVVRFVRILRIFKLTRHFVGL 341

  Fly   331 KILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNP-------HNDFNSIPLGLWWALV 388
            ::|..|.|||..|..||:.||.||::|||:::||||||...|       |.||.:||:|.|||:|
 Frog   342 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVV 406

  Fly   389 TMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLP 453
            ||||:|||||.|.|:.||.||||||||||||||:||||||:||.||||...|:.|||||:.:.:|
 Frog   407 TMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP 471

  Fly   454 VEQPRQPRLPGAPGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDLVSPKSVAQLFAGPLGAS 518
                 :|..||:|                            |....||.||...||..|.||...
 Frog   472 -----RPPQPGSP----------------------------NYCKPDLQSPHRSAQGDACPLAQE 503

  Fly   519 IV-----AMSPRTMLDLNPALAMGK-PTFQPRIPTPLAATPPPP--------------------- 556
            .:     |.|.:.....|.|||... ||....: :|...:|..|
 Frog   504 EIIEINRADSKQNGDAANAALANEDCPTIDQAL-SPEEKSPVTPGGRERYNRDRACFLLSTGDFA 567

  Fly   557 ----------------VSSAGGMTASGIGTTSATGATSAP--------QPATPLPSI 589
                            ::|..||:    |.|......|.|        :|.:|:|||
 Frog   568 HSPDGNIRKGYEKSRSLNSIAGMS----GNTLRLSPISTPFGSPSAVRRPRSPIPSI 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	70/101 (69%)
		BTB_2	27..117	CDD:280393	65/93 (70%)
		Ion_trans	244..439	CDD:278921	114/208 (55%)
		Ion_trans_2	355..429	CDD:285168	52/80 (65%)
LOC100497714	XP_012822914.1	Potassium_chann	1..29	CDD:314363
		BTB_KCNC1_3	34..150	CDD:349721	78/121 (64%)
		Ion_trans	199..457	CDD:366146	134/264 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	247	1.000	Domainoid score	I2104
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	458	1.000	Inparanoid score	I1532
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D331021at33208
OrthoFinder	1	1.000	-	-		FOG0000990
OrthoInspector	1	1.000	-	-		otm48109
Panther	1	1.100	-	-	O	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.070