DRSC/TRiP Functional Genomics Resources

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Protein Alignment Shaw and kcna2

DIOPT Version :9

Sequence 1:NP_001137782.1 Gene:Shaw / 33599 FlyBaseID:FBgn0003386 Length:619 Species:Drosophila melanogaster
Sequence 2:XP_031752644.1 Gene:kcna2 / 100496794 XenbaseID:XB-GENE-991578 Length:499 Species:Xenopus tropicalis


Alignment Length:463 Identity:176/463 - (38%)
Similarity:251/463 - (54%) Gaps:76/463 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 RVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRT-GKL 89
            |||:|:.|:|.||...||.:.|.|.|....:.:..:||:.|||||||:...|..:|.||:: |:|
 Frog    34 RVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRL 98

  Fly    90 HYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKF 154
            ..|.:|...:|.||:.|:.|....:|                   :.|.|....|..|..|.   
 Frog    99 RRPVNVPLDIFSEEIRFYELGEEAME-------------------IFREDEGFIKEEERPLP--- 141

  Fly   155 GFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHP------- 212
              :.:|.|           ::|.||:.|.||..|:.|.::||..|.|||:||||:|.|       
 Frog   142 --DNEYQK-----------QVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPVFRDENE 193

  Fly   213 DMRVPIVR-----NITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKW 272
            ||....|.     |.||:....:.  |.|        .||.:|.:|..||:||.||||.:.|:|.
 Frog   194 DMHGSGVNYYPYSNSTVRYQKSNT--FTD--------PFFIVETLCIIWFSFEFLVRFFACPSKA 248

  Fly   273 EFIKSSVNIIDYIATLSFYIDLVLQRFASHLENAD---------ILEFFSIIRIMRLFKLTRHSS 328
            .|..:.:||||.:|.:.::|.|..: .|...|:..         ||....::|:.|:|||:|||.
 Frog   249 GFFTNIMNIIDIVAIIPYFITLGTE-LAEKTEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSK 312

  Fly   329 GLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTV 393
            ||:||.||.:||.:||.||:|||.:|:::|:|.||:||..:.:  :.|.|||...|||:|:||||
 Frog   313 GLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERD--SQFPSIPDAFWWAVVSMTTV 375

  Fly   394 GYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPR 458
            |||||.|.|..|..||:|||:|||||||||||||||||..:| |.:...   :::.:.|.|..  
 Frog   376 GYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETEG---EEQAQYLQVTS-- 434

  Fly   459 QPRLPGAP 466
            .|::|.:|
 Frog   435 CPKIPSSP 442

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ShawNP_001137782.1 BTB 27..125 CDD:197585 35/98 (36%)
BTB_2 27..117 CDD:280393 35/90 (39%)
Ion_trans 244..439 CDD:278921 100/203 (49%)
Ion_trans_2 355..429 CDD:285168 44/73 (60%)
kcna2XP_031752644.1 BTB_POZ 33..159 CDD:365784 47/159 (30%)
Ion_trans 162..420 CDD:395416 122/271 (45%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X19
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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