DRSC/TRiP Functional Genomics Resources

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Protein Alignment Shaw and kcns1

DIOPT Version :9

Sequence 1:NP_001137782.1 Gene:Shaw / 33599 FlyBaseID:FBgn0003386 Length:619 Species:Drosophila melanogaster
Sequence 2:XP_002938059.3 Gene:kcns1 / 100492665 XenbaseID:XB-GENE-6051189 Length:451 Species:Xenopus tropicalis


Alignment Length:469 Identity:139/469 - (29%)
Similarity:231/469 - (49%) Gaps:65/469 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 ENRVVLNVGGIRHETYKATLKKIPATRLSRL---------TEALANYDPILNEYFFDRHPGVFAQ 79
            ::.:.:||||::......||.:.|.|||.||         .:...:||.:..|::|||:||:|..
 Frog    15 DHSININVGGMKKRISPITLLQFPDTRLGRLLSCDSEESILQICDDYDLVSKEFYFDRNPGLFPY 79

  Fly    80 VLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEK 144
            ||.:|.|||||...|:|...|.:|:|:||:....::.||  :|..|....|:..  ...|.|::.
 Frog    80 VLYFYETGKLHMMDDLCAFSFSQEIEYWGISEFFLDSCC--SYRYHERKLESRR--RNWDEDSDA 140

  Fly   145 PSEEELARKFG-FEED--YYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSF 206
            .|.|....:.. |.:|  |:...  ....::.|:|...:.|..|..:|....:|:..:.|||.:.
 Frog   141 SSIETSVDEISDFNQDIMYFDNV--QCGNLRKRLWLTMENPGYSIPSKIFSFISICVVLISISTM 203

  Fly   207 CLKTHPDMR------VPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRF 265
            |:.:.|:.:      .|:...|..|                       :|..|.:|||||:..|.
 Frog   204 CINSMPEYQQVDEDLAPVDDPILHK-----------------------LEYFCISWFTFEVSSRL 245

  Fly   266 ISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQ-RFASHLENAD---ILEFFSIIRIMRLFKLTRH 326
            :.:||..:|.:..:|:||.::.|.|||.|.:. .|.|..|..:   :::.|.::||.|:.||.||
 Frog   246 LLAPNLKKFFRHPLNLIDIVSVLPFYITLFIDLTFGSDYELGNVGKVVQVFRLMRIFRVLKLARH 310

  Fly   327 SSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMT 391
            |:||:.|..|.:.|.:|:.:|:.:|.:|:.:|:.:.|.||.   :....|::||...||..|:||
 Frog   311 STGLRSLGATLKHSYREVGILLLYLAVGVSVFSGMAYTAEM---DEDTGFDTIPSCWWWGTVSMT 372

  Fly   392 TVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQ 456
            ||||||:.|.|..|....:.|.|.|:|.:|||:.:|.:.|:.:|           :|::.|....
 Frog   373 TVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFSHFY-----------RRQKALENAV 426

  Fly   457 PRQPRLPGAPGGVS 470
            ....|:|.....||
 Frog   427 RNSDRIPREDSNVS 440

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ShawNP_001137782.1 BTB 27..125 CDD:197585 39/106 (37%)
BTB_2 27..117 CDD:280393 36/98 (37%)
Ion_trans 244..439 CDD:278921 71/198 (36%)
Ion_trans_2 355..429 CDD:285168 29/73 (40%)
kcns1XP_002938059.3 BTB_POZ_KCNS1 18..123 CDD:349733 39/106 (37%)
Ion_trans 185..420 CDD:395416 82/271 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D818306at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X19
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.920

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