Protein Alignment Shaw and kcnc2

DIOPT Version :9

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_002939991.2
• Gene: kcnc2 / 100489216
• XenbaseID: XB-GENE-1013657
• Length: 598
• Species: Xenopus tropicalis
• Alignment Length: 633
• Identity: 261/633 - (41%)
• Similarity: 357/633 - (56%)
• Gaps: 103/633 - (16%)

  Fly    21 MDSENRVVLNVGGIRHETYKATLKKIPATRLSRL--------------TEALANYDPILNEYFFD 71
            :|...|::|||||.|||||::|||.:|.|||:.|              .....|.....||:|||
 Frog     4 IDENERIILNVGGTRHETYRSTLKTVPGTRLALLACESQSEQGLDQQTVSGSFNITSRGNEFFFD 68

  Fly    72 RHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLD 136
            |||||||.|||||||||||.|.|||||||||||.|||:|...|||||||||.||||.:|.|.:.:
 Frog    69 RHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFE 133

  Fly   137 RLDLDTEKPS-----EEELARKFGFEE----DYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIG 192
            ..||.|.:|.     ||:|.::...|:    |   |.:..|:.::||:|:||::||||.||:.|.
 Frog   134 TPDLITGEPPPIDEYEEDLGKRLAIEDVVCPD---GKVGRWRRLQPRMWALFEDPYSSRAARFIA 195

  Fly   193 VVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWF 257
            ..|:|||.:||.:|||:||......|.:..||.  ||:....|.:.:|:.  |..|:|.||..||
 Frog   196 FASLFFILVSITTFCLETHEAFNTIINKTETVN--NGTELISLIEIETDP--ALTYVEGVCVVWF 256

  Fly   258 TFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSI---IRIMR 319
            |||.|||.|..|:|.|||::.:||||::|.|.||:::.|...:|.... |:|.|..:   :||:|
 Frog   257 TFEFLVRVIFCPDKLEFIRNLLNIIDFVAILPFYLEVGLSGLSSKAAK-DVLGFLRVVRFVRILR 320

  Fly   320 LFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNP-------HNDFN 377
            :||||||..||::|..|.|||..|..||:.||.||::|||:::||||||..:|       |..|.
 Frog   321 IFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPSDPSASKHTQFK 385

  Fly   378 SIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARA 442
            :||:|.|||:|||||:|||||.|:|:.||.||||||||||||||:||||||:||.||||...|:.
 Frog   386 NIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQ 450

  Fly   443 KLPKKRRRVLPVEQPRQPRLPGAPGGVS-----GC---------------------GTPGSGPHS 481
            |||:||::.:    |..|: .|:|....     ||                     |...||...
 Frog   451 KLPRKRKKYI----PHAPQ-TGSPTFCKMDLNMGCNSTQVDTCLGKDNRLMEHNMSGEDSSGSDQ 510

  Fly   482 GPMGSGGTGP-RRMNNKTKDLVSPKSVAQLFAGPLGASIVAMSPRTMLDLNPALAMGKPTFQPRI 545
             |:..|...| ||.:.:.|:..:            |...:..:.....:.:..:..|....:
 Frog   511 -PLSPGERYPIRRSSTRDKNRRT------------GTCFLLTTGEYTCNTDGGIRKGYEKSR--- 559

  Fly   546 PTPLAATPPPPVSSAGGMTASGIGTTSATGATSAPQP----ATPLPSI 589
                      .:::..|:..:.:..:..|...|:|.|    .:|:|||
 Frog   560 ----------SLNNIAGLAGNALRLSPVTSPYSSPCPLRRSRSPIPSI 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	67/111 (60%)
		BTB_2	27..117	CDD:280393	60/103 (58%)
		Ion_trans	244..439	CDD:278921	113/204 (55%)
		Ion_trans_2	355..429	CDD:285168	51/80 (64%)
kcnc2	XP_002939991.2	BTB_KCNC2_4	7..129	CDD:349722	73/121 (60%)
		Ion_trans	191..447	CDD:395416	133/260 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	247	1.000	Domainoid score	I2104
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H71199
Inparanoid	1	1.050	458	1.000	Inparanoid score	I1532
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D331021at33208
OrthoFinder	1	1.000	-	-		FOG0000990
OrthoInspector	1	1.000	-	-		otm48109
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060