DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shaw and kctd9

DIOPT Version :9

Sequence 1:	NP_001137782.1	Gene:	Shaw / 33599	FlyBaseID:	FBgn0003386	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_001120488.1	Gene:	kctd9 / 100145607	XenbaseID:	XB-GENE-976411	Length:	389	Species:	Xenopus tropicalis

Alignment Length:	133	Identity:	40/133 - (30%)
Similarity:	60/133 - (45%)	Gaps:	23/133 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 VVLNVGGIRHETYKATL-KKIPATRLSRL---TEALANYDPILNEYFFDRHPGVFAQVLNYYRTG 87
            :.|||||....|.::|| .|.|.:.||.:   .:|..|.......:..||.|..|..:|||.|.|
Frog    91 LTLNVGGRYFTTTRSTLVSKEPDSMLSHMFSDRDAWGNKKDHTGAFLIDRSPEYFEPILNYLRHG 155

  Fly    88 KL--HYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKP-SEEE 149
            :|  :...::.|.|  ||.:|:|:||          ..:|.:    ||:.:....|...| |.:|
Frog   156 QLIVNDGVNLLGVL--EEAKFFGIDS----------LIEHLE----LAIKNSQPADDHSPISRKE 204

  Fly   150 LAR 152
            ..|
Frog   205 FIR 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB	27..125	CDD:197585	32/103 (31%)
		BTB_2	27..117	CDD:280393	32/95 (34%)
		Ion_trans	244..439	CDD:278921
		Ion_trans_2	355..429	CDD:285168
kctd9	NP_001120488.1	KHA	2..64	CDD:288667
		BTB	90..191	CDD:197585	35/115 (30%)
		BTB	91..181	CDD:295341	32/101 (32%)
		Pentapeptide	219..251	CDD:279183
		Pentapeptide_4	240..325	CDD:290330
		Pentapeptide	243..280	CDD:279183
		Pentapeptide	303..342	CDD:279183
		Pentapeptide_4	310..384	CDD:290330
		Pentapeptide	338..377	CDD:279183
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910