Protein Alignment CG2818 and PHO81

DIOPT Version :10

• Sequence 1: NP_608804.1
• Gene: CG2818 / 33597
• FlyBaseID: FBgn0031566
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_011749.3
• Gene: PHO81 / 853148
• SGDID: S000003465
• Length: 1178
• Species: Saccharomyces cerevisiae
• Alignment Length: 771
• Identity: 151/771 - (19%)
• Similarity: 247/771 - (32%)
• Gaps: 283/771 - (36%)

  Fly    20 SCPASSENGSRLESRRIFGDITTNRLWTFRVLMNQDLAPNEQLAIVGNCEALGNWQHSGAAIL-- 82
            :|..::.:.::|             |...|...|.|.|.|:....:  |:.|.....:|...|
Yeast   514 ACKFNNHDAAKL-------------LLEIRSKQNADNAKNKSSQHL--CQPLFKKNSTGLCTLHI 563

  Fly    83 -------------------SKNEEDNEYSNLWTGEIYIPRHCDTEYRYMVCAV-----------D 117
                               ..||.|.  .|.||...|..|...:|   ::..:           |
Yeast   564 VAKIGGDPQLIQLLIRYGADPNEIDG--FNKWTPIFYAVRSGHSE---VITELLKHNARLDIEDD 623

  Fly   118 PGTEQLIVRRWETQLQPRIVKELDEQPAKNQSDIFGSFNGQEKVDR------------------- 163
            .|...|....||:.:.  ::..|.::|....|......|.|....|
Yeast   624 NGHSPLFYALWESHVD--VLNALLQRPLNLPSAPLNEINSQSSTQRLNTIDLTPNDDKFDLDIQD 686

  Fly   164 -------------------GWLTKETLVQLKFFYAPFTFKQRMKRRHIQ-VKVTPMNLSIPSAGC 208
                               .:|.|:..::||.            |..:: :|:|..|..|.|:..
Yeast   687 SIPDFALPPPIIPLRKYGHNFLEKKIFIKLKL------------RPGLESIKLTQDNGIIMSSSP 739

  Fly   209 DTMLPSSPMED-------------SLSNDTHDTKENGGESSTAFAFSEVVTLSADECEIRSQEQF 260
            ..:..||.:.:             .::|...|..|...|.              |:.||......
Yeast   740 GRITLSSNLPEIIPRNVILPVRSGEINNFCKDISETNDEE--------------DDDEISEDHDD 790

  Fly   261 GTGCGPTDLVIFHL-TVGDFENTAYLIDLYSYSSR-VAKEDGPPNHLGYHYVLPNLFKR----SE 319
            |.       :||.: ::.||.....:..  |:.:| :||..          .:|.|||:    |.
Yeast   791 GE-------IIFQVDSIDDFSMDFEIFP--SFGTRIIAKTT----------AMPFLFKKVAINSI 836

  Fly   320 GNLELPITCAKGHRPLGMMRLGYLIVKPSSLCALMDMSVSYARYWNSKWTGLDVGHRGSGTSFKA 384
            ..:.||:...:.:. :|.:.|.|.|:.|.....|  ..::|..||.|         .||.....:
Yeast   837 ATMNLPLFDTRLNN-IGSLTLDYQIIFPYPGNPL--KIINYEPYWKS---------TGSDLMTSS 889

  Fly   385 KDAVIRENTITSLKNAAEHGADMVEFDVQLSKDLVPVVYHDFMIYVSLKSKCSLQEHDFLALP-- 447
            ||.    |.:||               ..|:...:.|:.            |:|.:...:|.|
Yeast   890 KDG----NFVTS---------------SSLNGSFISVLV------------CALNDETIVAAPKP 923

  Fly   448 ----------MRELSLEQLKKLKVYHIA--EGLSRETRSFHNDDCLEHQ-------PFPQLCDVL 493
                      :.:|:.|||:|:..|...  :|      ||  |:....|       |...|.:|:
Yeast   924 YVEFKGTKILLNDLTKEQLEKVVDYDFGKIDG------SF--DEVTLKQYLSSRVVPLRSLLEVI 980

  Fly   494 DA---LDVHVGF-------NIEIKWSQRLEDGKMEEEFEHVVDRNLYIDCILDVI------LRKA 542
            ..   |.:.|.|       .|.||.|.             .::.|.:||.:|.:|      ||.:
Yeast   981 PGSAQLVIRVYFPTDKEIDTIPIKISP-------------FININQFIDKLLLIIFEHERFLRHS 1032

  Fly   543 GN---RRIVLSCFDPDICTILRFKQNRYPVM--FLTLGRTTKYQKYMDPRGNSM-ELA------- 594
            |:   |:||.|..:.:.|:||.:||..:||:  ...|.|.:...|::....|.: |||
Yeast  1033 GSGSMRQIVFSSCNWEACSILNWKQPNFPVLLQMKNLLRDSTTGKFVGDTPNCLKELAVNPQKMS 1097

  Fly   595 ------------VWHAVAMEFLGVVAHTEDLLRDPSQVNLAKERGLVLFCWGDDNN 638
                        |..|:....|||....|.|...||...:.|:.||:|.....:|:
Yeast  1098 YLNTELINIHTMVQFAMNNNLLGVTLPYEVLKICPSLARIIKQNGLLLIASVGEND 1153

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2818	NP_608804.1	CBM20_Prei4	44..166	CDD:99888	30/191 (16%)
		GDPD_GDE5	371..659	CDD:176549	74/330 (22%)
PHO81	NP_011749.3	SPX_PHO81_NUC-2_like	2..159	CDD:269904
		ANKYR	395..690	CDD:440430	32/197 (16%)
		ANK repeat	423..456	CDD:293786
		ANK repeat	458..495	CDD:293786
		ANK repeat	508..540	CDD:293786	7/38 (18%)
		ANK repeat	561..588	CDD:293786	3/26 (12%)
		ANK repeat	590..622	CDD:293786	6/34 (18%)
		GDPD_NUC-2_fungi	875..1172	CDD:176520	77/340 (23%)