Protein Alignment CG2818 and Gpcpd1

DIOPT Version :10

• Sequence 1: NP_608804.1
• Gene: CG2818 / 33597
• FlyBaseID: FBgn0031566
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_001342578.1
• Gene: Gpcpd1 / 74182
• MGIID: 104898
• Length: 682
• Species: Mus musculus
• Alignment Length: 679
• Identity: 244/679 - (35%)
• Similarity: 368/679 - (54%)
• Gaps: 72/679 - (10%)

  Fly    47 TFRVLMNQDLAPNEQLAIVGNCEALGNWQHSGA-AILSKNEEDNEYSNLWTGEIYIPRHCDTEYR 110
            ||.:  ...|.|.|..||.|:|:|||||....| |::::||..:  |.||...|.:.|....:||
Mouse     7 TFEI--RGTLLPGEVFAICGSCDALGNWNPQNAVALINENETGD--SVLWKAVIALNRGVSVKYR 67

  Fly   111 YM-VCAVDP----GTEQLIVRRWETQLQPRIVKELDEQPAKNQSDIFGSFNGQEKVDRGWLTKET 170
            |. .|.::|    |..|:||.:|||.||||.:..|:.:...:... ||..||.|.:|.||||.:|
Mouse    68 YFRGCFLEPKTIGGPCQVIVHKWETHLQPRSITPLESEIIIDDGQ-FGIHNGVETLDSGWLTCQT 131

  Fly   171 LVQLKFFYA---PFTF-KQRMKRRHIQVKVTPMNLSIPSAGCDTMLPSSP-----MEDSLSNDTH 226
            .::|:..::   |.:. |::.|:...:||:|...|.......|..:  ||     |.:||
Mouse   132 EIRLRLHFSEKPPVSISKKKFKKSRFRVKLTLEGLEEDEDDDDDKV--SPTVLHKMSNSL----- 189

  Fly   227 DTKENGGESSTAFAFSEVVTLSADECEIR-SQEQFGTGCGPTDLVIFHLTVGDFENTAYLIDLY- 289
                            |:..:|.:|.:.| ||.:.|.|..|.....:.:...:.:|...:.|.:
Mouse   190 ----------------EISLISDNEFKCRHSQPECGYGLQPDRWTEYSIQTMEPDNLELIFDFFE 238

  Fly   290 -SYSSRVAKEDGPPNHLGYHYVLPNLFK---RSEGNLELPITCAKGHRPLGMMRLGYLIVK--PS 348
             ..|..|.:.|..|.|:|...:|.:...   ||.|.|.|||......:.:|.:|:.::|:|  |.
Mouse   239 EDLSEHVVQGDVLPGHVGTACLLSSTIAESGRSAGILTLPIMSRNSRKTIGKVRVDFIIIKPLPG 303

  Fly   349 SLCALMDMSVSYARYWNSKWTGLDVGHRGSGTS-FKAKDAVIRENTITSLKNAAEHGADMVEFDV 412
            ..|:   |..|:::||..: ..|||||||:|.| ..||.|.::||||.||:|||.|||..|||||
Mouse   304 YSCS---MQSSFSKYWKPR-IPLDVGHRGAGNSTTTAKLAKVQENTIASLRNAASHGAAFVEFDV 364

  Fly   413 QLSKDLVPVVYHDFMIYVSLKSKCSLQEHDFLA-------LPMRELSLEQLKKLKVYHIAEGLSR 470
            .||||.|||||||....:::|.|..:....:.|       :|::||:.:||:.||:.|:....::
Mouse   365 HLSKDFVPVVYHDLTCCLTMKRKKFVHTQKYEADPVELFEIPVKELTFDQLQLLKLSHVTALKTK 429

  Fly   471 ETR-SFHNDDCL--EHQPFPQLCDVLDALDVHVGFNIEIKWSQRLEDGKMEEEFEHVVDRNLYID 532
            :.: |.:.::..  |:||||.|..||::|..:|||||||||..:..||..:.......|.|:::|
Mouse   430 DRKQSLYEEENFFSENQPFPSLKMVLESLPENVGFNIEIKWICQHRDGVWDGNLSTYFDMNVFLD 494

  Fly   533 CILDVILRKAGNRRIVLSCFDPDICTILRFKQNRYPVMFLTLGRTTKYQKYMDPRGNSMELAVWH 597
            .||..:|..:|.||||.|.||.||||::|.|||:||::|||.|::..|.:.||.|..:..:|:..
Mouse   495 IILKTVLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQGKSDIYPELMDLRSRTTPIAMSF 559

  Fly   598 AVAMEFLGVVAHTEDLLRDPSQVNLAKERGLVLFCWGDDNNSKDTIKLLKELGLHAIIYDKMDVL 662
            |.....||:.||||||||:||.|..||.:|||:||||||.|..:..:.|||.|::.:|||:  :.
Mouse   560 AQFENILGINAHTEDLLRNPSYVQEAKAKGLVIFCWGDDTNDPENRRKLKEFGVNGLIYDR--IY 622

  Fly   663 TTKEVKQSVFHLQAKDSQKELLKLQALEM 691
            .....:.::|.::    |.|.||.:..|:
Mouse   623 DWMPEQPNIFQVE----QLERLKQELPEL 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2818	NP_608804.1	CBM20_Prei4	44..166	CDD:99888	47/124 (38%)
		GDPD_GDE5	371..659	CDD:176549	138/298 (46%)
Gpcpd1	NP_001342578.1	CBM20_Prei4	4..127	CDD:99888	47/124 (38%)
		GDPD_GDE5	322..621	CDD:176549	138/300 (46%)