Protein Alignment IM33 and COL7A1

DIOPT Version :10

• Sequence 1: NP_608800.1
• Gene: IM33 / 33592
• FlyBaseID: FBgn0031561
• Length: 82
• Species: Drosophila melanogaster
• Sequence 2: NP_000085.1
• Gene: COL7A1 / 1294
• HGNCID: 2214
• Length: 2944
• Species: Homo sapiens
• Alignment Length: 63
• Identity: 29/63 - (46%)
• Similarity: 38/63 - (60%)
• Gaps: 11/63 - (17%)

  Fly    22 DPICGLPAGIDGNGLIKCAAFIPSFSYH----PETNSCEKFIYGGCGGNENRFGTQELCEQKC 80
            || |.||.. :|:    |.|:...: ||    ..|.:|..|:|||||||.|||||:|.||::|
Human  2874 DP-CSLPLD-EGS----CTAYTLRW-YHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IM33	NP_608800.1	Kunitz_SCI-I-like	24..80	CDD:438677	26/59 (44%)
COL7A1	NP_000085.1	Nonhelical region (NC1)	17..1253
		vWA_collagen_alphaI-XII-like	37..201	CDD:238759
		fn3	233..317	CDD:394996
		FN3	301..813	CDD:442628
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	632..651
		fn3	777..855	CDD:394996
		FN3	867..952	CDD:238020
		FN3	955..1044	CDD:238020
		VWA	1054..1227	CDD:459670
		Cell attachment site. /evidence=ECO:0000255	1170..1172
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1239..1941
		Triple-helical region	1254..2784
		gly_rich_SclB	<1254..1565	CDD:468478
		Interrupted collagenous region	1254..1477
		Cell attachment site. /evidence=ECO:0000255	1334..1336
		gly_rich_SclB	<1447..>1693	CDD:468478
		gly_rich_SclB	<1637..>1881	CDD:468478
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1963..2782
		Cell attachment site. /evidence=ECO:0000255	2008..2010
		gly_rich_SclB	<2022..>2365	CDD:468478
		gly_rich_SclB	<2287..>2569	CDD:468478
		gly_rich_SclB	<2481..>2718	CDD:468478
		Cell attachment site. /evidence=ECO:0000255	2553..2555
		Collagen	2737..2783	CDD:460189
		Nonhelical region (NC2)	2785..2944		29/63 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2837..2872
		Kunitz_collagen_alpha1_VII	2874..2929	CDD:438670	28/61 (46%)