DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment odd and MSN2

DIOPT Version :9

Sequence 1:	NP_722922.1	Gene:	odd / 33583	FlyBaseID:	FBgn0002985	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_013751.1	Gene:	MSN2 / 855053	SGDID:	S000004640	Length:	704	Species:	Saccharomyces cerevisiae

Alignment Length:	310	Identity:	69/310 - (22%)
Similarity:	110/310 - (35%)	Gaps:	113/310 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 NLSREQDFAEEDFI------VIKEERETSLS---PMLTPPHTPTEEPLRRVHPAISEEAVATQLH 74
            |||..|.|.:...|      ||.:...|.||   |.|      |||..:..:...:.:...||::
Yeast   480 NLSSSQQFIKPSMILSDNASVIAKVATTGLSNDMPFL------TEEGEQNANSTPNFDLSITQMN 538

  Fly    75 MRHMAHYQQQQQQQQQQQQHRLWLQMQQQQQQHQAPQQYPVYPTASADPVAVHQQLMNHWIRNAA 139
            |.                                     |:.|.:|:..    ....||:.
Yeast   539 MA-------------------------------------PLSPASSSST----SLATNHFY---- 558

  Fly   140 IYQQQQQQQQHPHHHHHHGHPHHPHPHPHHVRPYPAGLHSLHAAV---MGRHFGAMP---TLKL- 197
                        ||....||                  |::::.:   :.|...|:|   |:.|
Yeast   559 ------------HHFPQQGH------------------HTMNSKIGSSLRRRKSAVPLMGTVPLT 593

  Fly   198 -------GGAGGASGVPSGATGSSRPKKQFICKYCNRQFTKS--YNLLIHERTHTDERPYSCDIC 253
                   ..:..::|..:|.|...||      .|..:..|.|  .:::|......:|:|:.|.||
Yeast   594 NQQNNISSSSVNSTGNGAGVTKERRP------SYRRKSMTPSRRSSVVIESTKELEEKPFHCHIC 652

  Fly   254 GKAFRRQDHLRDH-RYIHSKDKPFKCSDCGKGFCQSRTLAVHKVTHLEEG 302
            .|:|:|.:||:.| |.:||.::||.|..|.|.|.:|..|:.|..||.:.|
Yeast   653 PKSFKRSEHLKRHVRSVHSNERPFACHICDKKFSRSDNLSQHIKTHKKHG 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
odd	NP_722922.1	COG5048	<203..334	CDD:227381	35/103 (34%)
		C2H2 Zn finger	222..242	CDD:275368	4/21 (19%)
		zf-H2C2_2	234..259	CDD:290200	8/24 (33%)
		C2H2 Zn finger	250..270	CDD:275368	10/20 (50%)
		zf-H2C2_2	262..285	CDD:290200	11/23 (48%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		zf-C2H2	304..326	CDD:278523
		C2H2 Zn finger	306..326	CDD:275368
MSN2	NP_013751.1	COG5048	127..594	CDD:227381	34/194 (18%)
		zf-C2H2_4	647..670	CDD:404733	10/22 (45%)
		C2H2 Zn finger	649..670	CDD:275368	10/20 (50%)
		zf-H2C2_2	661..687	CDD:404364	12/25 (48%)
		zf-C2H2	676..698	CDD:395048	8/21 (38%)
		C2H2 Zn finger	678..698	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030