DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment odd and Osr2

DIOPT Version :9

Sequence 1:	NP_722922.1	Gene:	odd / 33583	FlyBaseID:	FBgn0002985	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_017450351.1	Gene:	Osr2 / 315039	RGDID:	1305812	Length:	312	Species:	Rattus norvegicus

Alignment Length:	277	Identity:	121/277 - (43%)
Similarity:	146/277 - (52%)	Gaps:	61/277 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 PQQYPVYPT----------------ASADPV-------AVHQQLMNHW---------IRNAAIYQ 142
            |...|::|:                |:.|.:       ||....||||         |..:.|.:
  Rat     7 PAPIPLHPSLQLTNYSFLQAVNTFPAAVDHLQGLYGLSAVQTMHMNHWTLGYPNVHEITRSTITE 71

  Fly   143 QQQQQ----QQHPH---------HHHHHGHPHHPHPHPHHVRPYPAGLHSLHAAVMGRH-----F 189
            ....|    .:.|.         .|...|...|..|..|..||   .....:.||....     .
  Rat    72 MAAAQGLVDARFPFPALPFATHLFHPKQGAIAHVLPALHKDRP---RFDFANLAVAATQEDPPKM 133

  Fly   190 GAMPTLKLGGAGGASGV--------PSGATGSSRPKKQFICKYCNRQFTKSYNLLIHERTHTDER 246
            |.:..|..|.....||:        ||.....|:.||:||||:|.|.||||||||||||||||||
  Rat   134 GDLSKLSPGLGSPISGLSKLTPDRKPSRGRLPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDER 198

  Fly   247 PYSCDICGKAFRRQDHLRDHRYIHSKDKPFKCSDCGKGFCQSRTLAVHKVTHLEEGPHKCPICQR 311
            ||:||||.||||||||||||||||||:|||||.:|||||||||||||||..|::|.|||||.|.|
  Rat   199 PYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQESPHKCPTCGR 263

  Fly   312 SFNQRANLKSHLQSHSE 328
            :||||:|||:||.:|::
  Rat   264 TFNQRSNLKTHLLTHTD 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
odd	NP_722922.1	COG5048	<203..334	CDD:227381	94/134 (70%)
		C2H2 Zn finger	222..242	CDD:275368	16/19 (84%)
		zf-H2C2_2	234..259	CDD:290200	22/24 (92%)
		C2H2 Zn finger	250..270	CDD:275368	18/19 (95%)
		zf-H2C2_2	262..285	CDD:290200	19/22 (86%)
		C2H2 Zn finger	278..298	CDD:275368	16/19 (84%)
		zf-C2H2	304..326	CDD:278523	15/21 (71%)
		C2H2 Zn finger	306..326	CDD:275368	13/19 (68%)
Osr2	XP_017450351.1	C2H2 Zn finger	174..194	CDD:275368	16/19 (84%)
		zf-H2C2_2	186..211	CDD:404364	22/24 (92%)
		C2H2 Zn finger	202..222	CDD:275368	18/19 (95%)
		zf-H2C2_2	214..237	CDD:404364	19/22 (86%)
		C2H2 Zn finger	230..250	CDD:275368	16/19 (84%)
		COG5048	251..>312	CDD:227381	18/30 (60%)
		C2H2 Zn finger	258..278	CDD:275368	13/19 (68%)
		C2H2 Zn finger	286..306	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I11040
eggNOG	1	0.900	-	-		E33208_3B9IA
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000748
OrthoInspector	1	1.000	-	-		mtm8926
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14196
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1664
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.870