DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment odd and prz1

DIOPT Version :9

Sequence 1:	NP_722922.1	Gene:	odd / 33583	FlyBaseID:	FBgn0002985	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_593073.1	Gene:	prz1 / 2541806	PomBaseID:	SPAC4G8.13c	Length:	681	Species:	Schizosaccharomyces pombe

Alignment Length:	418	Identity:	92/418 - (22%)
Similarity:	140/418 - (33%)	Gaps:	123/418 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TSASP-ISNITVD---DELNLSREQDF----AEEDFIVIKE---ERETSLSPMLTPPHTPT---- 53
            |:||| .||..:|   |..||:...|.    :...||....   |.....||.|.|....|
pombe   294 TNASPGESNTGIDFDTDNTNLNPSVDLLSNHSTPSFIFENSPSAEFSHQSSPYLVPNSGRTLNSE 358

  Fly    54 ---EEPLRRVHPAISEEAVATQL--HM----------RHMAHYQQQQQQQQQQQQHRLWLQMQQQ 103
               |..:|.|:...||:.....|  |:          ..:.:|.........|..     .:...
pombe   359 NARESTIRSVNSPFSEDHADASLTTHVFDPISPTALSNSVLNYDSNNFSGTPQIN-----VVPSS 418

  Fly   104 QQQHQAPQQYPVYP----------TASADPVAVHQQLMN---HWIRNAAIYQQQQQQQQHPHHHH 155
            ..:.|:....|..|          :.||.||: .|..||   :.::||.:...:........|..
pombe   419 PSKSQSGPSLPANPLLQTDISITYSQSASPVS-GQPAMNENSYDLQNANLCAPEMSPTYTARHRS 482

  Fly   156 HHG-------------HPHHPHPHP---------------------------HHVRPYPAGLHSL 180
            :..             :.|..|...                           .:.||....|:||
pombe   483 NSAGSRFDAYEPIPQLYTHFSHSSECLSVNQDTELLGKIENDNSKSNDYLSVRNTRPRSRSLNSL 547

  Fly   181 HAAVMGRHFGAMPTLKLGGAGGASGVPSGATGSSRPKKQ--FICKY--CNRQFTKSYNLLIHERT 241
                               .|..|...|.:...|..|.|  ::|.:  ||::||::|||..|..|
pombe   548 -------------------VGNKSENSSSSKAKSESKSQGNYVCTFAGCNKRFTRAYNLKSHMNT 593

  Fly   242 HTDERPYSCDICGKAFRRQDHLRDHRYIHSKDKPFKCSDCGKGFCQSRTLAVHKVTHLEEGPHKC 306
            ||:.||:.|.||.|:|.||...|.|..:|:..|.|.|..|.:.|.:...|..|..:.:.:.
pombe   594 HTNYRPFQCSICKKSFARQHDKRRHEQLHTGIKAFACVTCNQRFARMDALNRHYKSEVGQN---- 654

  Fly   307 PICQRSFNQRA-----NLKSHLQSHSEQ 329
              |.|:..:|.     :.|:.:.|.|:|
pombe   655 --CLRTATERGIQVPPSRKTAVASTSKQ 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
odd	NP_722922.1	COG5048	<203..334	CDD:227381	43/136 (32%)
		C2H2 Zn finger	222..242	CDD:275368	9/21 (43%)
		zf-H2C2_2	234..259	CDD:290200	13/24 (54%)
		C2H2 Zn finger	250..270	CDD:275368	9/19 (47%)
		zf-H2C2_2	262..285	CDD:290200	7/22 (32%)
		C2H2 Zn finger	278..298	CDD:275368	5/19 (26%)
		zf-C2H2	304..326	CDD:278523	4/26 (15%)
		C2H2 Zn finger	306..326	CDD:275368	4/24 (17%)
prz1	NP_593073.1	COG5048	121..620	CDD:227381	77/350 (22%)
		zf-C2H2	570..594	CDD:278523	9/23 (39%)
		C2H2 Zn finger	577..594	CDD:275368	8/16 (50%)
		zf-H2C2_2	586..611	CDD:290200	13/24 (54%)
		C2H2 Zn finger	602..622	CDD:275368	9/19 (47%)
		zf-H2C2_2	616..639	CDD:290200	8/22 (36%)
		C2H2 Zn finger	630..648	CDD:275368	5/17 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030