DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment odd and Osr1

DIOPT Version :9

Sequence 1:	NP_722922.1	Gene:	odd / 33583	FlyBaseID:	FBgn0002985	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_035989.1	Gene:	Osr1 / 23967	MGIID:	1344424	Length:	266	Species:	Mus musculus

Alignment Length:	265	Identity:	101/265 - (38%)
Similarity:	117/265 - (44%)	Gaps:	88/265 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 PVAVHQQLMNHWIRNAAIYQQQQQQQQHPHHH-------------HHH----GHP--HHPHP--- 165
            ||.:|..|.   :.|.:..|........|..|             |.|    |:|  |.|..
Mouse     9 PVPIHPSLQ---LTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFS 70

  Fly   166 ---------------------HPHHVRPYPAGLHSLHAAVMGRHFGAMPTLKLG----------- 198
                                 .||.:.|.|    .:.|...|......|.....
Mouse    71 KVPGAVSSLMDARFQLPAFPWFPHVIHPKP----EITAGGSGAALKTKPRFDFANLALAATQEDP 131

  Fly   199 ---GAGGASGVPSGATGS-------------------SRPKKQFICKYCNRQFTKSYNLLIHERT 241
               |.|...|.|:|..|:                   |:.||:|:||:|.|.|||||||||||||
Mouse   132 TKLGRGEGPGSPAGGLGALLDVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERT 196

  Fly   242 HTDERPYSCDICGKAFRRQDHLRDHRYIHSKDKPFKCSDCGKGFCQSRTLAVHKVTH-----LEE 301
            |||||||:||||.||||||||||||||||||:|||||.:|||||||||||||||..|     |:.
Mouse   197 HTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKT 261

  Fly   302 GPHKC 306
            ...||
Mouse   262 SKIKC 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
odd	NP_722922.1	COG5048	<203..334	CDD:227381	78/128 (61%)
		C2H2 Zn finger	222..242	CDD:275368	16/19 (84%)
		zf-H2C2_2	234..259	CDD:290200	22/24 (92%)
		C2H2 Zn finger	250..270	CDD:275368	18/19 (95%)
		zf-H2C2_2	262..285	CDD:290200	19/22 (86%)
		C2H2 Zn finger	278..298	CDD:275368	16/19 (84%)
		zf-C2H2	304..326	CDD:278523	2/3 (67%)
		C2H2 Zn finger	306..326	CDD:275368	1/1 (100%)
Osr1	NP_035989.1	zf-C2H2	175..197	CDD:395048	17/21 (81%)
		C2H2 Zn finger	177..197	CDD:275368	16/19 (84%)
		zf-H2C2_2	189..214	CDD:404364	22/24 (92%)
		C2H2 Zn finger	205..225	CDD:275368	18/19 (95%)
		zf-H2C2_2	217..240	CDD:404364	19/22 (86%)
		C2H2 Zn finger	233..253	CDD:275368	16/19 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I11278
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2594
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000748
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14196
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	1	1.000	-	-		X1664
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.950