DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment odd and egr1

DIOPT Version :9

Sequence 1:	NP_722922.1	Gene:	odd / 33583	FlyBaseID:	FBgn0002985	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001090830.1	Gene:	egr1 / 100038164	XenbaseID:	XB-GENE-853412	Length:	499	Species:	Xenopus tropicalis

Alignment Length:	356	Identity:	81/356 - (22%)
Similarity:	119/356 - (33%)	Gaps:	89/356 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 SPMLTPPHTPTEEPLRRV------HPAISEEAVATQLHMRHMAHYQQQQQQQQQQQQHRLWLQMQ 101
            ||.|.|..:|  :|.:..      :|..:.....|...:..:..|...|||.............|
Frog   184 SPELFPDQSP--QPFQNASTASIPYPPPAYPVSKTTFQVPMIPDYLFPQQQGDVSLVSADQKPFQ 246

  Fly   102 QQQQQHQAPQQYPVYPTASADPVAVHQQLMNHWIRNAAIYQQQQQQQQHPHHHHHHGHPHHPHPH 166
            ..:.:.|.|...|: .|..|......|.|       ..|....|.|...|.....  :|:.|...
Frog   247 AMESRTQQPSLTPL-STIKAFATQTSQDL-------KTINSTYQSQIIKPSRMRK--YPNRPSKT 301

  Fly   167 PHHVRPYPAGLHSLHAAVMGRHFGAMPTLKLGGAGGASGVPSGATGSSRPKKQFICKYCNRQFTK 231
            |.|.|||...:.|                                             |:|:|::
Frog   302 PPHERPYACPVES---------------------------------------------CDRRFSR 321

  Fly   232 SYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKDKPFKCSDCGKGFCQSRTLAVHKV 296
            |..|..|.|.||.::|:.|.||.:.|.|.|||..|...|:.:|||.|..||:.|.
Frog   322 SDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFA---------- 376

  Fly   297 THLEEGPHKCPICQRSFNQRANLKSHLQSHSEQSTKEVVVT-TSPATSHSVPNQALSSPQPENLA 360
                          ||..::.:.|.||:...:::.|...|: .||.:|:| |:.:.|.|.|...:
Frog   377 --------------RSDERKRHTKIHLRQKDKKADKATPVSVASPVSSYS-PSASTSYPSPVPTS 426

  Fly   361 QHLPVLDLSSSSSSSEKPKRMLGFTIDEIMS 391
            ...||.....|...|..|......|...:.|
Frog   427 YSSPVSSAYPSPVHSSFPSPTTAVTYPSVTS 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
odd	NP_722922.1	COG5048	<203..334	CDD:227381	33/130 (25%)
		C2H2 Zn finger	222..242	CDD:275368	7/19 (37%)
		zf-H2C2_2	234..259	CDD:290200	10/24 (42%)
		C2H2 Zn finger	250..270	CDD:275368	9/19 (47%)
		zf-H2C2_2	262..285	CDD:290200	10/22 (45%)
		C2H2 Zn finger	278..298	CDD:275368	4/19 (21%)
		zf-C2H2	304..326	CDD:278523	5/21 (24%)
		C2H2 Zn finger	306..326	CDD:275368	5/19 (26%)
egr1	NP_001090830.1	DUF3446	106..180	CDD:288757
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	288..309		7/22 (32%)
		zf-C2H2	308..332	CDD:278523	9/68 (13%)
		C2H2 Zn finger	310..332	CDD:275368	8/66 (12%)
		zf-H2C2_2	324..349	CDD:290200	10/24 (42%)
		C2H2 Zn finger	340..360	CDD:275368	9/19 (47%)
		zf-H2C2_2	352..377	CDD:290200	11/48 (23%)
		C2H2 Zn finger	368..388	CDD:275368	7/43 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	379..423		12/44 (27%)
		DUF3432	401..486	CDD:288743	16/58 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940