Protein Alignment sob and OSR2

DIOPT Version :10

• Sequence 1: NP_476882.1
• Gene: sob / 33581
• FlyBaseID: FBgn0004892
• Length: 578
• Species: Drosophila melanogaster
• Sequence 2: NP_001273770.1
• Gene: OSR2 / 116039
• HGNCID: 15830
• Length: 433
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 162/339 - (47%)
• Similarity: 196/339 - (57%)
• Gaps: 53/339 - (15%)

  Fly   232 PPLTAATASAAATSS-PSSNNSNSTSTPTTSKCVP---------LPSIGTVSAAVAAAAAAAAAA 286
            ||.:.:.......|: |:|....|.:.|......|         |.::.|..|.|.........:
Human   101 PPASDSWKKGLVPSAPPASRKMGSKALPAPIPLHPSLQLTNYSFLQAVNTFPATVDHLQGLYGLS 165

  Fly   287 ASQQAALD-------------CATAAELAAECDLPLLDGE---DALSFEAGDLDSSYGSFMFNPS 335
            |.|...::             .:|..|:||.  ..|:|..   .||.|.         :.:|:|.
Human   166 AVQTMHMNHWTLGYPNVHEITRSTITEMAAA--QGLVDARFPFPALPFT---------THLFHPK 219

  Fly   336 AFSQAETDSALH---------SLQATMYQD---KMSVISGAAGGVGAGAVGGLEEAGSSAAAAAA 388
            ..:.|....|||         :|.....|:   ||..:|..:.|:|: .:.||.:.......:..
Human   220 QGAIAHVLPALHKDRPRFDFANLAVAATQEDPPKMGDLSKLSPGLGS-PISGLSKLTPDRKPSRG 283

  Fly   389 Q---RSKKQFICKFCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKEKP 450
            :   ::||:||||||.|.||||||||||||||||||||:||||.|||||||||||||||||||||
Human   284 RLPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKP 348

  Fly   451 FKCAECGKGFCQSRTLAVHKILHMEESPHKCPVCNRSFNQRSNLKTHLLTHTDIKPYNCASCGKV 515
            |||.||||||||||||||||.|||:|||||||.|.|:||||||||||||||||||||:|..||||
Human   349 FKCQECGKGFCQSRTLAVHKTLHMQESPHKCPTCGRTFNQRSNLKTHLLTHTDIKPYSCEQCGKV 413

  Fly   516 FRRNCDLRRHSLTH 529
            ||||||||||||||
Human   414 FRRNCDLRRHSLTH 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sob	NP_476882.1	COG5048	<389..529	CDD:227381	122/142 (86%)
		C2H2 Zn finger	397..417	CDD:275368	17/19 (89%)
		zf-H2C2_2	409..434	CDD:463886	22/24 (92%)
		C2H2 Zn finger	425..445	CDD:275368	18/19 (95%)
		zf-H2C2_2	437..460	CDD:463886	21/22 (95%)
		C2H2 Zn finger	453..473	CDD:275368	17/19 (89%)
		C2H2 Zn finger	481..501	CDD:275368	16/19 (84%)
		C2H2 Zn finger	509..529	CDD:275368	17/19 (89%)
OSR2	NP_001273770.1	COG5048	<293..428	CDD:227381	122/135 (90%)
		C2H2 Zn finger	295..315	CDD:275368	17/19 (89%)
		C2H2 Zn finger	323..343	CDD:275368	18/19 (95%)
		C2H2 Zn finger	351..371	CDD:275368	17/19 (89%)
		C2H2 Zn finger	379..399	CDD:275368	16/19 (84%)
		C2H2 Zn finger	407..427	CDD:275368	17/19 (89%)