Protein Alignment CG8852 and LOC4576485

DIOPT Version :10

• Sequence 1: NP_608790.2
• Gene: CG8852 / 33577
• FlyBaseID: FBgn0031548
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: XP_061503426.1
• Gene: LOC4576485 / 4576485
• VectorBaseID: AGAMI1_009834
• Length: 481
• Species: Anopheles gambiae
• Alignment Length: 483
• Identity: 116/483 - (24%)
• Similarity: 200/483 - (41%)
• Gaps: 103/483 - (21%)

  Fly    14 VFLVVVSQILSHVRAAG--DAMSSANESISLPPA-----------CVIRATL-YKTSSSERSQND 64
            |..|||..:|:..::|.  ..::..|||::|...           |:|..|: |:....|.:.|
Mosquito     3 VLQVVVIMLLTSRKSANCQSVVNHNNESVNLSTQNDWRCARLLNHCLIVTTVNYRVPGKEFAIN- 66

  Fly    65 FGLPLAIDCS----ENSSMGMNYFDLGAQRVAGKRHVSLDGFQTPPLGISSYGLEYL---DNCVD 122
                  .||:    :|:.....:..:.:.|:.|:...|..||          |||||   |....
Mosquito    67 ------FDCNVHPVKNAHSDKVFRKVTSYRMDGRNAYSDTGF----------GLEYLSFPDKITT 115

  Fly   123 L----ESVEIQRFVGDATLKLSCGGALIP------NLTAVSFRYNELGTLSGETIQDLPHLKILH 177
            |    ..|.:||              .:|      ||..:......:..::|:..||||.|:.|.
Mosquito   116 LVLHGYCVRMQR--------------AVPLYRDFHNLELLELINCNVNHINGDVFQDLPKLQKLV 166

  Fly   178 LQQNSLRYL--EYFKEHSDLEELLIQDERDLVLRFNEILN-QLPELRRLSLRNVEKIED------ 233
            |..::...:  :.|.:...|:|:.|::...:....::::| ||..:|..::..:..|.|
Mosquito   167 LNSSTFGVMTHDVFHKLIQLKEMFIENCTGIQFTASDLVNIQLIAVRNSTVYQISSIFDYLPSTL 231

  Fly   234 ---QFLRILPENLTDLIIENTPIQPGVLYLTEGVAKLVNVTITNCQLKGFALQPAHNLDIMYLNL 295
               .|:.:|...:.::.:.::..:...:.....|..|::..|.....:           ::.|||
Mosquito   232 KTINFVNVLTHEIPNITLRSSDEEQSAVEDVAVVQSLLSCVIVKSLPR-----------LISLNL 285

  Fly   296 SGNAISSLNISFESGPSTLLTLDLSRNRLEHLNFTWFYRTTSLRSLHLQEN---HFHSLSLFQLG 357
            |.|::|..:|...:.|| |:||.||.|....::...|...:||..|.|..|   :.|..:
Mosquito   286 SRNSLSENSIVLHNLPS-LVTLVLSHNGFNQVSVALFASGSSLNVLDLSHNQISYIHPKA----- 344

  Fly   358 FISSASIHHIDLRSNELMSFRDTEN-ADLPSWNPQLRISIDDNPWSCQWMLNFSHMQPQLFRLFQ 421
            |.||..:..::|..|.|:|.   || |.||...   ||.||.|||.|.|:.....:.|.||.:|:
Mosquito   345 FSSSPLLRMVNLSYNLLLSM---ENFAPLPRLE---RIEIDKNPWDCLWLTKCRVINPSLFEIFR 403

  Fly   422 YSKYISHININGLSCTPQEPP--SEEPP 447
            |||....:::.||.|..::..  |..||
Mosquito   404 YSKRYDVLSVWGLPCRLEDTKEISTSPP 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8852	NP_608790.2	LRR	<122..452	CDD:443914	86/354 (24%)
		leucine-rich repeat	149..172	CDD:275380	5/22 (23%)
		leucine-rich repeat	173..194	CDD:275380	4/22 (18%)
		leucine-rich repeat	220..242	CDD:275380	5/30 (17%)
		leucine-rich repeat	243..266	CDD:275380	1/22 (5%)
		leucine-rich repeat	267..287	CDD:275380	2/19 (11%)
		leucine-rich repeat	288..313	CDD:275380	8/24 (33%)
		leucine-rich repeat	314..337	CDD:275380	7/22 (32%)
		leucine-rich repeat	364..387	CDD:275378	8/23 (35%)
		leucine-rich repeat	392..403	CDD:275378	7/10 (70%)
LOC4576485	XP_061503426.1	None