Protein Alignment CG8852 and iglr-1

DIOPT Version :10

• Sequence 1: NP_608790.2
• Gene: CG8852 / 33577
• FlyBaseID: FBgn0031548
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_510491.2
• Gene: iglr-1 / 184720
• WormBaseID: WBGene00008977
• Length: 695
• Species: Caenorhabditis elegans
• Alignment Length: 408
• Identity: 91/408 - (22%)
• Similarity: 136/408 - (33%)
• Gaps: 144/408 - (35%)

  Fly   106 PLGISSYGLEYLDNCVDLESVEIQRFVGDATLKLSCGGALIPNLTAVSFRYNELGTLSGETIQ-- 168
            |||.|..  |...:|..|...|:..|:  ..||.|              .:||...||..:|.
 Worm    23 PLGCSCN--ESSISCTFLTKPELYVFL--EVLKDS--------------PFNETTDLSLASIDNF 69

  Fly   169 ------DLPHLKILHLQQN-SLRYLEYFKEHSDLEELLIQDERDLVLRFNEILNQLPELRRLSLR 226
                  |:|.|::|.:|.: ||                  |:.|..||    .||.|||:.|..:
 Worm    70 WLRMLPDMPKLRVLKVQSSPSL------------------DDSDWFLR----RNQFPELQTLHFK 112

  Fly   227 NVEKIEDQFLRILPENLTDLIIENTPIQPGVLYLTEGVAKLVNVTITNCQLKGFALQPAHNLDIM 291
            |..      |:..|:.|..|                  ..|:.:.:::..|:.......|...|.
 Worm   113 NCS------LKTFPKALMAL------------------TSLLELDLSDNMLENLGADSIHIRSIQ 153

  Fly   292 YLNLSGNAISSLNISFESGPSTLLTLDLSRNRLEHLNFTWFYRTTSLRSLHLQENHFHSLS---- 352
            .:.|..|.|.|:.:.......||..||||.|.:..|..:.|....|||.|.|:||....:.
 Worm   154 RVILRNNQIKSIGVHVFRYMPTLKMLDLSGNNMTRLVTSDFTSAVSLRELILRENKIELIETDTT 218

  Fly   353 ---------------LFQLGFISSASIHH---IDLRSNELMSFR-------DTENADLPSWN--- 389
                           |.::...:..:..|   ::|..|.|...|       |.:...|.:.|
 Worm   219 EPMQQLETLDLSGNLLSEVRLEAQQNFRHLFSLNLSCNPLQIIREGFLQLPDLQVLQLDNCNISV 283

  Fly   390 ---------PQLR-ISIDDNPWSCQWMLNFSHMQPQLF-------RL-FQYSKY----------I 426
                     |:|. :.|.|||       |.::..|..|       |: .|.|.:          |
 Worm   284 VEAGAFVSLPRLHSMDIKDNP-------NLAYFSPYAFSNNTAFYRMNIQNSGFKRIPLTILEKI 341

  Fly   427 SHINING----LSCTPQE 440
            |.:.|.|    .|||.::
 Worm   342 SQLYIKGTQLDCSCTSRD 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8852	NP_608790.2	LRR	<122..452	CDD:443914	85/392 (22%)
		leucine-rich repeat	149..172	CDD:275380	6/30 (20%)
		leucine-rich repeat	173..194	CDD:275380	5/21 (24%)
		leucine-rich repeat	220..242	CDD:275380	5/21 (24%)
		leucine-rich repeat	243..266	CDD:275380	2/22 (9%)
		leucine-rich repeat	267..287	CDD:275380	2/19 (11%)
		leucine-rich repeat	288..313	CDD:275380	5/24 (21%)
		leucine-rich repeat	314..337	CDD:275380	8/22 (36%)
		leucine-rich repeat	364..387	CDD:275378	7/32 (22%)
		leucine-rich repeat	392..403	CDD:275378	5/11 (45%)
iglr-1	NP_510491.2	LRR	<102..346	CDD:443914	57/274 (21%)
		leucine-rich repeat	106..128	CDD:275380	7/45 (16%)
		leucine-rich repeat	129..151	CDD:275380	3/21 (14%)
		leucine-rich repeat	152..175	CDD:275380	5/22 (23%)
		leucine-rich repeat	176..199	CDD:275380	8/22 (36%)
		leucine-rich repeat	200..223	CDD:275380	6/22 (27%)
		leucine-rich repeat	224..247	CDD:275380	1/22 (5%)
		leucine-rich repeat	248..270	CDD:275380	4/21 (19%)
		leucine-rich repeat	271..294	CDD:275380	2/22 (9%)
		leucine-rich repeat	295..316	CDD:275380	8/27 (30%)
		leucine-rich repeat	320..343	CDD:275380	4/22 (18%)