DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CIV and Mamdc2

DIOPT Version :9

Sequence 1:	NP_608789.1	Gene:	Sr-CIV / 33576	FlyBaseID:	FBgn0031547	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_036017587.1	Gene:	Mamdc2 / 71738	MGIID:	1918988	Length:	689	Species:	Mus musculus

Alignment Length:	233	Identity:	67/233 - (28%)
Similarity:	94/233 - (40%)	Gaps:	44/233 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 PMKAKII----CSD--GHGLVGNRIAYCDGEKWSTQLGSC--ALRRQTIDVSCDFESEDMCGWTA 144
            ||..|::    |..  ..|||..       :..:.|||:|  ..|.......|.|: :|.|.:|.
Mouse   467 PMPTKVVFMSLCKSFWDCGLVAL-------DDITIQLGNCRSPARLPPPPGECTFD-QDECAFTQ 523

  Fly   145 ELSFLGTWKRVSTVADFHSEKTGPQKDHTFQNQSIGHYVRMETESDAFG-TYHFLSPLYPKELSL 208
            |.....:|.|..  .:..:..|||:.|||   ..:|:|:.:|.....:| ..|.||.      .|
Mouse   524 EKRNRSSWHRGR--GETPTSYTGPKGDHT---TGVGYYMYIEASHMVYGQKAHLLSQ------PL 577

  Fly   209 SGA----CFQFHYFMFGSGVGSLLVSIKPVSVTIGDIFKTNHPYKFDQFVMTGSQGARWLEHTID 269
            .|.    |..|.|.|:|:|.|.|.|.:|....:...:.          :...|.|...||...::
Mouse   578 RGVPGKHCLTFFYHMYGAGTGLLSVYLKREEDSEESLL----------WRRRGEQSISWLRALVE 632

  Fly   270 INKMDEDFQVIFTATDARSQYGDIAIDDVKLMAAKECA 307
            .: .....|:||.||...|...|||||||||.|. .||
Mouse   633 YS-CRRRHQIIFEATRGVSIRSDIAIDDVKLQAG-PCA 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIV	NP_608789.1	MAM	132..306	CDD:279023	53/178 (30%)
		MAM	132..301	CDD:99706	51/173 (29%)
		Somatomedin_B	336..376	CDD:279385
Mamdc2	XP_036017587.1	MAM	26..170	CDD:99706
		MAM	173..330	CDD:395504
		MAM	345..499	CDD:99706	10/38 (26%)
		MAM	512..667	CDD:99706	53/178 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8224
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860