DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CIV and mep1a.2

DIOPT Version :9

Sequence 1:	NP_608789.1	Gene:	Sr-CIV / 33576	FlyBaseID:	FBgn0031547	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001122199.1	Gene:	mep1a.2 / 565535	ZFINID:	ZDB-GENE-041001-208	Length:	689	Species:	Danio rerio

Alignment Length:	208	Identity:	47/208 - (22%)
Similarity:	86/208 - (41%)	Gaps:	26/208 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 HGLVGNRIAY--CDGEKWSTQLGSCALRRQTIDVSCDFESEDMCGWTAELSFLGTWKRVSTVADF 161
            :.::|.|:.:  .|.|:.: ::..|......:| .|.||..::||..........|.:..:..|.
Zfish   231 NNIIGQRLDFSALDLERLN-RMYECTATHTLLD-QCAFEQINICGMIQNDEDDADWVQTLSSTDL 293

  Fly   162 HSEKTGPQKDHTF--QNQSIGHYVRMETESDAFGTYHFLSP--LYPKELSLSGACFQFHYFMFGS 222
                    ||||.  |.:..|::::.:|::...|....|..  ||||.   :..|.:|.|.|.|.
Zfish   294 --------KDHTLGGQCRDSGYFMKFDTDNKTEGHSALLESRILYPKR---NQQCLEFFYRMSGE 347

  Fly   223 GVGSLLVSIKPVSVTIGDIFKTNHPYKFDQFVMTGSQGARWLEHTIDINKMDEDFQVIFTATDAR 287
            ....|::.::....| |::.|....:     .:||.....|....:.:| :.|.|:..|......
Zfish   348 PGDKLIIWVRTDDGT-GNVNKVRKVH-----TITGHGDNSWNIAQVTLN-VKEKFRYFFQGIVGP 405

  Fly   288 SQYGDIAIDDVKL 300
            ::...|.|||:.|
Zfish   406 NKTSGIFIDDIIL 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIV	NP_608789.1	MAM	132..306	CDD:279023	41/173 (24%)
		MAM	132..301	CDD:99706	41/173 (24%)
		Somatomedin_B	336..376	CDD:279385
mep1a.2	NP_001122199.1	ZnMc	26..254	CDD:294052	4/23 (17%)
		Astacin	68..256	CDD:279708	5/25 (20%)
		MAM	259..423	CDD:214533	42/179 (23%)
		MAM	264..423	CDD:99706	41/173 (24%)
		MATH	423..579	CDD:295307
		EGF	619..653	CDD:278437
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I5116
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.050