DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CIV and nrp2b

DIOPT Version :9

Sequence 1:	NP_608789.1	Gene:	Sr-CIV / 33576	FlyBaseID:	FBgn0031547	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_998131.1	Gene:	nrp2b / 405902	ZFINID:	ZDB-GENE-040611-3	Length:	920	Species:	Danio rerio

Alignment Length:	226	Identity:	55/226 - (24%)
Similarity:	96/226 - (42%)	Gaps:	47/226 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 CDFESEDMCGWTAE-LSFLGTWKRVSTVADFHSEKTGPQKDHTFQNQSIGHYVRMETE--SDAFG 193
            |||| :.|||||.: :|.| .|...|:        :.|..|.|....:.|:::.:|..  |:. .
Zfish   630 CDFE-QSMCGWTHDPMSDL-KWSMYSS--------SSPSLDLTHGPDNFGNFLYVEASPMSEP-Q 683

  Fly   194 TYHFLSPLYPKELSLSGACFQFHYFMFGSGVGSLLVSIKPVSVTIGDIFKTNHPYKFDQ-----F 253
            ....|||....|..|  .|..|:|.:.|:|..||.|.::                ..||     :
Zfish   684 RARLLSPSVGPERRL--VCLLFYYQLRGAGQESLRVLLR----------------DDDQEETLLW 730

  Fly   254 VMTGSQGARWLEHTIDINKMDEDFQVIFTATDARSQYGDIAIDDVKLMAA---KECARRSTFIEE 315
            .:.|.||:.|.|....:.:..:::||:......|...|.|.||::.:.::   ::|.:  .|...
Zfish   731 TLKGDQGSMWREGRTILPQSPKEYQVVIEGFFERGSRGHIRIDNIHMSSSIELEQCTQ--PFAAF 793

  Fly   316 PKKPIEE--SDITDSLGYQMTDCSGRCGQDF 344
            |.:..|.  .|:.::..::..|   |.||::
Zfish   794 PPEMTERRPEDLGNNRLFKGRD---RIGQEY 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIV	NP_608789.1	MAM	132..306	CDD:279023	46/184 (25%)
		MAM	132..301	CDD:99706	46/176 (26%)
		Somatomedin_B	336..376	CDD:279385	3/9 (33%)
nrp2b	NP_998131.1	CUB	26..139	CDD:238001
		CUB	146..261	CDD:238001
		FA58C	276..423	CDD:238014
		FA58C	436..588	CDD:238014
		MAM	630..779	CDD:366209	46/177 (26%)
		DUF3481	842..920	CDD:371830
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9895
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000