Protein Alignment Sr-CIV and Mamdc4

DIOPT Version :10

• Sequence 1: NP_608789.1
• Gene: Sr-CIV / 33576
• FlyBaseID: FBgn0031547
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_001074668.2
• Gene: Mamdc4 / 381352
• MGIID: 2685841
• Length: 1232
• Species: Mus musculus
• Alignment Length: 312
• Identity: 73/312 - (23%)
• Similarity: 122/312 - (39%)
• Gaps: 64/312 - (20%)

  Fly    87 APMKA--KIICSDGHGLVGNRIAYCDGEKWSTQLG-SCALRRQTIDVSCDFESEDMCGWTAELSF 148
            :|:||  ..:|..|.         |..|   ||.| ..|....:...:|:|| :|.||| .::|.
Mouse    35 SPIKAVCNFVCDCGD---------CSDE---TQCGFHGASTIPSTSFTCNFE-QDSCGW-QDIST 85

  Fly   149 LG-TWKRVSTVADFHSEKTGPQKDHTFQNQSIGHYVRMETESDAF-GTYHFLSPLYPKELSLSGA 211
            .| .|.|....|..|.  .||..||| ....:|.|:.:.|.|... .|....||:..:   .:..
Mouse    86 SGYRWLRDRAGAVLHG--PGPHSDHT-HGTDLGWYMAVGTHSGKEPSTATLRSPVMRE---AAPT 144

  Fly   212 C-FQFHYFMFGSGVGSLLVSIKPVSVTIGDIFKTNHPYKFDQFVMTGSQGARWLEHTIDINKMDE 275
            | .:..|.:....|..|.:.:.....|: .:::|:.|:           |..|.|..::..::..
Mouse   145 CELRLWYHIASRDVAELRLDLTHGVETL-TLWQTSGPW-----------GPGWQELAVNTGRIQG 197

  Fly   276 DFQVIFTATDARSQYGDIAIDDVKLMAAKECARRSTFIEEPKKPIEESDITDSL---GYQMTDCS 337
            ||:|.|:||...:..|.:|:|||:.   ::|...   |.:.:.|:......:..   .:|:.|..
Mouse   198 DFKVTFSATRNATHRGAVALDDVEF---RDCGLP---IPQARCPLGHHHCQNKACVEPHQLCDGE 256

  Fly   338 GRCGQDFVRGRYINEGCRCQESCLVNGNCCLNYVKECHKDLVIAPYNELKFW 389
            ..||.            |..|..|:   |..:...:....|  .|:|:|:.|
Mouse   257 DNCGD------------RSDEDPLI---CSHHMATDFETGL--GPWNQLEGW 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIV	NP_608789.1	PHA02927	<19..>115	CDD:222943	7/29 (24%)
		MAM	132..301	CDD:459878	46/171 (27%)
		Somatomedin_B	336..377	CDD:460034	6/40 (15%)
Mamdc4	NP_001074668.2	MAM	66..224	CDD:214533	46/180 (26%)
		LDLa	234..266	CDD:238060	6/43 (14%)
		MAM	254..427	CDD:214533	12/55 (22%)
		LDLa	462..495	CDD:238060
		MAM	498..652	CDD:459878
		MAM	660..817	CDD:214533
		MAM	823..978	CDD:459878
		MAM	978..1144	CDD:214533