DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CIV and mdga2a

DIOPT Version :9

Sequence 1:	NP_608789.1	Gene:	Sr-CIV / 33576	FlyBaseID:	FBgn0031547	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_021328869.1	Gene:	mdga2a / 368826	ZFINID:	ZDB-GENE-030616-360	Length:	964	Species:	Danio rerio

Alignment Length:	190	Identity:	54/190 - (28%)
Similarity:	84/190 - (44%)	Gaps:	31/190 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 CDFESEDMCGWTAELSFLGTWKR--VSTVADFHSEKTGPQKDHTFQNQSIGHYVRMET-----ES 189
            |.||.:.:|.:|.:.:....|.|  .:|....::..|||..|.:...|  |.|:.:||     |.
Zfish   755 CGFEEDTICMFTQDKTEEFDWTRHSAATRDTKYTPNTGPSSDRSGSKQ--GFYMYIETSRPRLEG 817

  Fly   190 DAFGTYHFLSPLY---PKE-----LSLSGACFQFHYFMFGSGVGSLLVSIKPVSVTIGDIFKTNH 246
            |   ....|:|.:   ||.     .|....||.|:|.|:|..:|:|.|.::..|.|..|.
Zfish   818 D---KARLLTPSFNVAPKNPYGNVASNPTYCFSFYYHMYGKHIGTLNVYLRQKSQTGQDT----- 874

  Fly   247 PYKFDQFVMTGSQGARWLEHTIDINKMDEDFQVIFTATDARSQYGDIAIDDVKLMAAKEC 306
                ..:.::|:||.||.:..::||. ...||::..........||||:|||.:... ||
Zfish   875 ----SVWTLSGNQGDRWRQARVNINP-TSSFQIVMEGIRGSGIEGDIAVDDVTIEEG-EC 928

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIV	NP_608789.1	MAM	132..306	CDD:279023	52/188 (28%)
		MAM	132..301	CDD:99706	52/183 (28%)
		Somatomedin_B	336..376	CDD:279385
mdga2a	XP_021328869.1	Ig_3	50..114	CDD:316449
		IG	154..223	CDD:214652
		IGc2	257..318	CDD:197706
		I-set	350..421	CDD:333254
		Ig_3	442..517	CDD:316449
		MAM	755..929	CDD:306977	54/190 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9895
eggNOG	1	0.900	-	-		E1_2CMY0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900