DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CIV and Nrp2

DIOPT Version :9

Sequence 1:	NP_608789.1	Gene:	Sr-CIV / 33576	FlyBaseID:	FBgn0031547	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001070871.1	Gene:	Nrp2 / 18187	MGIID:	1100492	Length:	931	Species:	Mus musculus

Alignment Length:	216	Identity:	48/216 - (22%)
Similarity:	90/216 - (41%)	Gaps:	50/216 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 SCDFE-SEDMCGWTAELSFLGTWKRVSTVADFHSEKTGPQKDHTFQNQSIGHYVRMETESDAFGT 194
            :|:|: .|:.|||..:.:   .|.|.:.::      :....|.||.:..  ::::::::....|.
Mouse   645 NCNFDFPEETCGWVYDHA---KWLRSTWIS------SANPNDRTFPDDK--NFLKLQSDGRREGQ 698

  Fly   195 Y-HFLSPLYPKELSLSGACFQFHYFMFGSGVGSLLVSIKPVSVTIGDIFKTNHPYKFDQFVMTGS 258
            | ..:||  |..|..|..|.:|.|...| |.|..|..::..|.....:           :|:...
Mouse   699 YGRLISP--PVHLPRSPVCMEFQYQAMG-GHGVALQVVREASQESKLL-----------WVIRED 749

  Fly   259 QGARWLEHTIDINKMDEDFQVIFTATDARSQYGDIAIDDVKLMAAKECARRSTFIEEPKKPIEES 323
            ||:.|....|.:...|.::|::|.....:.:.|:|:|||:::         ||.:     |:|..
Mouse   750 QGSEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEISIDDIRI---------STDV-----PLENC 800

  Fly   324 DITDSLGYQMTDCSGRCGQDF 344
                     |...|...|:||
Mouse   801 ---------MEPISAFAGEDF 812

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIV	NP_608789.1	MAM	132..306	CDD:279023	39/175 (22%)
		MAM	132..301	CDD:99706	39/170 (23%)
		Somatomedin_B	336..376	CDD:279385	4/9 (44%)
Nrp2	NP_001070871.1	CUB	28..141	CDD:238001
		CUB	149..265	CDD:238001
		FA58C	277..427	CDD:214572
		FA58C	280..426	CDD:238014
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	298..317
		FA58C	433..592	CDD:214572
		FA58C	438..591	CDD:238014
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	601..621
		MAM	641..794	CDD:214533	40/182 (22%)
		MAM	646..793	CDD:99706	39/180 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..854
		DUF3481	849..928	CDD:152415
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910