DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CIV and Cd55

DIOPT Version :9

Sequence 1:	NP_608789.1	Gene:	Sr-CIV / 33576	FlyBaseID:	FBgn0031547	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_006529178.1	Gene:	Cd55 / 13136	MGIID:	104850	Length:	471	Species:	Mus musculus

Alignment Length:	151	Identity:	38/151 - (25%)
Similarity:	62/151 - (41%)	Gaps:	23/151 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLWAIV--LISSVDRTNARCLESVHLEHGSTEIVNGSIIFHCDQGYFLQG-SKVFTCDRGIP--- 61
            |:|:.|  ........|.:.|::.|:...:..:....|.|.|:.||.|.| |..|....|..
Mouse   149 LVWSPVAQFCKKKSCPNPKDLDNGHINIPTGILFGSEINFSCNPGYRLVGVSSTFCSVTGNTVDW 213

  Fly    62 RGKKPFCAKSGCQEYEQIQNGFV---LNAPMKAKII---CSDGHGLVGNRIAYC-----DGEKWS 115
            ..:.|.|.:..|.|..:|.||.:   .::...::::   |..|..||||...||     |..:||
Mouse   214 DDEFPVCTEIHCPEPPKINNGIMRGESDSYTYSQVVTYSCDKGFILVGNASIYCTVSKSDVGQWS 278

  Fly   116 TQLGSC------ALRRQTIDV 130
            :....|      ..::.||:|
Mouse   279 SPPPRCIEKSKVPTKKPTINV 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIV	NP_608789.1	MAM	132..306	CDD:279023
		MAM	132..301	CDD:99706
		Somatomedin_B	336..376	CDD:279385
Cd55	XP_006529178.1	CCP	36..95	CDD:153056
		PHA02927	98..>292	CDD:222943	35/142 (25%)
		Glycoprotein_G	<285..361	CDD:144411	3/15 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	78	1.000	Inparanoid score	I5225
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050