DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CIV and mep1b

DIOPT Version :9

Sequence 1:	NP_608789.1	Gene:	Sr-CIV / 33576	FlyBaseID:	FBgn0031547	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001096352.1	Gene:	mep1b / 100124942	XenbaseID:	XB-GENE-1001365	Length:	722	Species:	Xenopus tropicalis

Alignment Length:	212	Identity:	51/212 - (24%)
Similarity:	82/212 - (38%)	Gaps:	29/212 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 LVGNRIAYCDG--EKWSTQLGSCALRRQTIDVSCDFESEDMCGWTAELSFLGTWKRVSTVADFHS 163
            ::|.|:.:.|.  ||.: :|.:|:.....:| ||.||..::||..........|..|...|
Frog   234 VIGQRMDFSDYDLEKLN-RLYNCSSSISFMD-SCTFEYNNICGMIQGTGDNSDWNHVLLSA---- 292

  Fly   164 EKTGPQKDHTFQN--QSIGHYVRMETESDAFGTYHFLSP--LYPKELSLSGACFQFHYFMFGSGV 224
              .||..|||...  :..|:|:...|.:...|....|..  .|||.   ...|.:|.|:..|:..
Frog   293 --AGPSNDHTHLGNCKDSGYYMHFSTSTGNAGDKALLESRLFYPKR---GFQCLEFFYYYNGNEN 352

  Fly   225 GSLLVSIKPVSVTIGDIFKTNHPYKFDQFV--MTGSQGARWLEHTIDINKMDEDFQVIFTATDAR 287
            .:|.:.|:.        :....|.....|:  :.|:....|..|.:.:| :...|:|:|......
Frog   353 DALNIWIRE--------YTEASPNGTLTFITSIKGNPAEYWQLHHVSLN-VKNKFRVVFEGVKGN 408

  Fly   288 S-QYGDIAIDDVKLMAA 303
            . ..|..||||:....|
Frog   409 GPSNGGFAIDDINFSEA 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CIV	NP_608789.1	MAM	132..306	CDD:279023	42/179 (23%)
		MAM	132..301	CDD:99706	41/175 (23%)
		Somatomedin_B	336..376	CDD:279385
mep1b	NP_001096352.1	ZnMc	26..255	CDD:412141	6/21 (29%)
		MAM	265..428	CDD:395504	42/179 (23%)
		MATH	427..590	CDD:351761
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910