Protein Alignment CG8851 and ODF2L

DIOPT Version :10

• Sequence 1: NP_722917.2
• Gene: CG8851 / 33575
• FlyBaseID: FBgn0031546
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_001353710.1
• Gene: ODF2L / 57489
• HGNCID: 29225
• Length: 644
• Species: Homo sapiens
• Alignment Length: 651
• Identity: 137/651 - (21%)
• Similarity: 256/651 - (39%)
• Gaps: 125/651 - (19%)

  Fly   105 TSSSNTSMGLDFELDEKNEDQADENEK---SSYVSLSRPSSKVLDTRSASSLDFGDHCSPSITKL 166
            ||.|:.|......|:||.|.:|...|.   :..|.|..|..|  ||....:.:     :.:::.|
Human    31 TSESHLSCLKQDILNEKTELEATLKEAELVTHSVELLLPLFK--DTIEKINFE-----NANLSAL 88

  Fly   167 PKNSREGKEVSLIMSDEEPEDYRKGLGSKRRLPDSEALGSKLKEELCKYKQELKDYNES-----T 226
            .....|.||: ||...:..:..:..|....|..|.:..|..|...|.   :.|.| |||     .
Human    89 NLKISEQKEI-LIKELDTFKSVKLALEHLLRKRDYKQTGDNLSSMLL---ENLTD-NESENTNLK 148

  Fly   227 KDLEEKYMKINYELCEMQQKHDQFVSSRKQAQQMDL----------GSEPDPDGFYSSASSVTSQ 281
            |.:.||...|....|..|.:....:.:.:.:|.:.:          ..|.:.|.......|:  :
Human   149 KKVFEKEAHIQELSCLFQSEKANTLKANRFSQSVKVVHERLQIQIHKREAENDKLKEYVKSL--E 211

  Fly   282 TTIRRKSPQILRSNTSFMTVLSGQSSCDEIDRKKYASERSTHQQNHHRHK-DDLPSQVNSVFDSR 345
            |.|.:.:.| .|.|.:...|:...|....:..|| ||:....:.:|.... :.|.||:... :::
Human   212 TKIAKWNLQ-SRMNKNEAIVMKEASRQKTVALKK-ASKVYKQRLDHFTGAIEKLTSQIRDQ-EAK 273

  Fly   346 IVETLANRHVKR---RKRSLEQDDREREPASFKDVYNVLKDVINTSQDQKYKHERDRGR------ 401
            :.||::..:..:   .|..:|:.:.|.:..:.|      |.:||..:|.| |.| |.|:
Human   274 LSETISASNAWKSHYEKIVIEKTELEVQIETMK------KQIINLLEDLK-KME-DHGKNSCEEI 330

  Fly   402 -------DRDRDRDSGDISQLLTTIKGLKSEQV-------QFRTLIRQQQERISDYHTRCVKAQD 452
                   :.:.:..:.:.::|.||:..||.|.|       :.:.:.::|:..|..|.|:..|.|:
Human   331 LRKVHSIEYENETLNLENTKLKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQE 395

  Fly   453 IMSTQKQEIEKLHVNNKQLESSIYHDIDSLRSKIDNKLKSVSHL--------------------- 496
            .....|...|.|...|.|:..:...:::.:|.::::.||.:..:
Human   396 AAEIVKSRCENLLHKNNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQESLQCC 460

  Fly   497 -PKMMRDEHSKYE---------------TVMRENCLLADKLHALQQEAMQLKVKIDELGRRKLVT 545
             .|....||:..|               ::..||||:..|...|||:..|:..:..||.:
Human   461 KGKCADQEHTIRELQGQVDGNHNLLTKLSLEEENCLIQLKCENLQQKLEQMDAENKELEK----- 520

  Fly   546 INRLKAAERDLKIFKNYNSALKTEKRKLTQELSTMKDQLEQLQASSKRQLSRHREQSEKQRRDLQ 610
              :|...|..||     :|.||.:::  :.|.:.:..|||......:::::...|:...:...||
Human   521 --KLANQEECLK-----HSNLKFKEK--SAEYTALARQLEAALEEGRQKVAEEIEKMSSRESALQ 576

  Fly   611 KKIYDLELKLSRSQNSTSSLI-------QERDSLIAELQTQLHTLVHNFEVSQKHIRVLRRHIYS 668
            .||.|||.:|.:.....:.|:       |.::..:.|:|..|....:..|..:.:::.|:....:
Human   577 IKILDLETELRKKNEEQNQLVCKMNSKAQHQEVCLKEVQNSLEKSENQNESIKNYLQFLKTSYVT 641

  Fly   669 M 669
            |
Human   642 M 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8851	NP_722917.2	SMC_prok_B	<430..>666	CDD:274008	56/279 (20%)
ODF2L	NP_001353710.1	SMC_prok_B	<135..443	CDD:274008	66/321 (21%)
		SMC_N	<340..>596	CDD:481474	56/269 (21%)