Protein Alignment CG8851 and LOC5668337

DIOPT Version :10

• Sequence 1: NP_722917.2
• Gene: CG8851 / 33575
• FlyBaseID: FBgn0031546
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_061518490.1
• Gene: LOC5668337 / 5668337
• VectorBaseID: AGAMI1_006294
• Length: 677
• Species: Anopheles gambiae
• Alignment Length: 677
• Identity: 136/677 - (20%)
• Similarity: 263/677 - (38%)
• Gaps: 179/677 - (26%)

  Fly   140 PSSKVLD-------TRSASSLDFGDHCSPSITKLPKNSREGKEVSLIMSDEEPEDYRKGLGSKRR 197
            ||.::.|       ||:|      :|.|.|:..:.::.|..|   |....:...::...|  ||:
Mosquito    30 PSGELDDDAAGPPSTRTA------NHPSASVAAIQQSKRLAK---LKQKLDRQNNFMVEL--KRK 83

  Fly   198 LPDSEALGSKL---KEELCKYKQELKDYNESTKDLEEKYMKINYELCEMQQ-------------- 245
            :.:.||:..|.   :|||...:..||      |:.|.::..:...:.|.:|
Mosquito    84 IREKEAMKPKADCDREELAFLRNRLK------KEAELQHKLLADVIAEQRQEGANQWQSIPLCPD 142

  Fly   246 KHDQFVSSRKQAQQMDLGSEPDPD----GFYSSASSVTSQTTIRRKSP-------------QILR 293
            |.|::.     |....:||.|..:    ...|:.|:::|...:..:.|             :.|.
Mosquito   143 KLDEYC-----ANPWTIGSVPVGEDRRFSIDSTLSALSSDELVGGEMPAGCTDAKLVERFEKELM 202

  Fly   294 SNTSFMTVLSGQSSCDEIDRKKYASERSTHQQNHHRH---------KDDLPSQVNSVFDSRIVET 349
            :....:.:|.|:......|..|...:..|....|.:.         :.|:..::.  |.....||
Mosquito   203 NRDRVIEILQGRLDRLSADVHKVRRDNDTILDRHPKPVAPITPRFCETDMMQRLE--FYRTNTET 265

  Fly   350 LAN--RHVKRRKRSLEQD----DRERE-----PASFKDVYNV----------------------- 380
            |..  ..::|...:::|:    .||.|     .|..|..::|
Mosquito   266 LGQNLEEMERALHTIQQELGPMGRESECPVKAAACAKPSHSVCEKSPARKSMSYSRPSVAHGRAS 330

  Fly   381 ----------LKDVINTSQD--------------------------QKYKHERDRGR-------- 401
                      |::.:..|..                          |:|..:....|
Mosquito   331 TFCDMSESCPLRESVAPSTTCPMRESVAPAVCPKDGEAQKQYTMLLQEYTKKTTECRQLCERLAK 395

  Fly   402 -----------DRDRDRDSGDISQLLTTIKGLKSEQVQFRTLIRQQQERISDYHTRCVKAQDIMS 455
                       |.:|:......|:||       .||.:||.|||:|..::.||..|.:.||..:.
Mosquito   396 AQAGPEDPTPEDTERELLKKRCSELL-------DEQDEFRVLIREQATQLDDYRARYLAAQQQVE 453

  Fly   456 TQKQEIEKLHVNNKQLESSIYHDIDSLRSKIDNKLKSVSHLPKMMRDEHSKYETVMREN-CLLAD 519
            .|:.::.||.|.|:::|..|..:|:.::.|..:||:.::..|:::.||.:|.|.:.:.| .|.|:
Mosquito   454 EQRLQMSKLQVTNRRVEKQINFEIEQIKRKFQDKLRHLTPYPRLLEDEQAKAEQLKQSNETLFAE 518

  Fly   520 KLHALQQEAMQLKVKIDELGRRKLVTINRLKAA----ERDLKIFKNYNSALKTEKRKLTQELSTM 580
                |::...|:|...|.|.:..:.....:|.|    :.||:..:.....:..||:::.:|....
Mosquito   519 ----LERSLRQVKTLEDRLHQVHVAKDTEVKQALLQSQTDLEQTQERLDVMAKEKQQVEEEAIRW 579

  Fly   581 KDQLEQLQASSKRQLSRHREQSEKQRRDLQKKIYDLELKLSRSQNSTSSLIQERDSLIAELQTQL 645
            :.:|::|:..|.:.:.|..::.||:|...||:...||.:|::.:...|..|..|:..:.|:.:|:
Mosquito   580 QRELDELRTESAKIIERANQRVEKERETAQKRYSQLESELAQCRAEASFTIGNREQALREMHSQI 644

  Fly   646 HTLVHNFEVSQKHIRVLRRHIYSMTNQ 672
            ..|..:|:.:|..||.||..:..:.|:
Mosquito   645 KVLSSSFDDAQLQIRSLRNQLAYLQNE 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8851	NP_722917.2	SMC_prok_B	<430..>666	CDD:274008	65/240 (27%)
LOC5668337	XP_061518490.1	None