Protein Alignment CG8851 and Odf2

DIOPT Version :10

• Sequence 1: NP_722917.2
• Gene: CG8851 / 33575
• FlyBaseID: FBgn0031546
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_017171761.1
• Gene: Odf2 / 18286
• MGIID: 1098824
• Length: 875
• Species: Mus musculus
• Alignment Length: 863
• Identity: 172/863 - (19%)
• Similarity: 317/863 - (36%)
• Gaps: 246/863 - (28%)

  Fly    49 RHLFGET-----NNYI------YYCRYLNWFK---------------IKTQCDLKEMMLKPSRR- 86
            |.|.|.|     |::|      ..||  :||.               ::|.|....:.:..|.:
Mouse    28 RRLHGTTLASDFNDFIRRRFWAQPCR--SWFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSHKR 90

  Fly    87 ----PLANRQRSLRFR---PQNRKGTSSSNTSMGLDFE-----------LDEK------NEDQAD 127
                ...|.:||:|.:   |....|.||:. .:|..:|           ..||      ..|.:.
Mouse    91 GMKGDTVNVRRSVRVKTKVPWMPPGKSSAR-HVGCKWENPPHCLEITPPSSEKLVSVMRLSDLST 154

  Fly   128 ENEKSSYVSLSRPSSKVLDTRSASSLDFGDHCSPSITKLPKNSR------------EGKEVSLIM 180
            |::.|.:..::|...|:      .||.....|..|..|:.|..|            |.:||:..:
Mouse   155 EDDDSGHCKMNRYDKKI------DSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHEL 213

  Fly   181 SDEEPE---------------DYRKGLGSKRRLPDSEALGSK-----------------LKEELC 213
            ::.|.|               |:.. |..|....:.|.|.||                 ||:.:.
Mouse   214 AETEHENTVLRHNIERIKEEKDFTM-LQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIG 277

  Fly   214 KYKQELK----DYNESTKDLEEKYMKI------NYELCE-MQQKHDQFVSSRKQAQQM------- 260
            |.|.|.:    |.|..|:..|....|:      |..|.: ::::|.:...|.:..:|.
Mouse   278 KLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEKDSERLMEQQGTLLKRL 342

  Fly   261 -DLGSE--------PDPDGFYSS-ASSVTSQTTIRRKSPQILRSNTSFMTVLSGQSSCDEIDRKK 315
             :..||        .|.|..... ...:..:....:.:.::.:|..|....|..|..|.|.:..:
Mouse   343 AEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSR 407

  Fly   316 YASERSTHQQNHHRHKDDLPSQVNSVFD---------SRIVETLANRHVKRRKRSLEQDDRERE- 370
            ...:....:::.::||    ::|.::.:         .|..||| .:.::.:|...|:.:...|
Mouse   408 LCMQIKNLERSGNQHK----AEVEAIMEQLKELKQKGDRDKETL-KKAIRAQKERAEKSEEYAEQ 467

  Fly   371 ---PASFKDVY----------------NVLK-----------------DVINTSQ--DQKYKHER 397
               ..:.||:|                .|:|                 |::|..|  ::|.:.:|
Mouse   468 LHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDR 532

  Fly   398 DRGRDRDRDRDSGDISQLLTTIKGLKS--------------EQVQFRTLIRQQQERISDYHTRCV 448
            |...:| ..|.:.:.|......:.||:              |..|.:..::..:..|.:|.::.:
Mouse   533 DSLVER-LHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVM 596

  Fly   449 KAQDIMSTQKQEIEKLHVNNKQLESSIYHDIDSLRSKIDNKLKSVSHLPKMMR----------DE 503
            |.:........::|:....||.|:..:..:|::.|.:..::|..:..||.:::          |:
Mouse   597 KTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQ 661

  Fly   504 HSKYETVMRENCLL--------------ADKL-------HALQQEAMQLKVKIDELGRRKLVT-- 545
            ...||   |:|..|              .|||       .|.|:|..||..|:|||.|:...|
Mouse   662 LQGYE---RKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSQKVDELERKLEATSA 723

  Fly   546 --INRLKA-AERDLKIFKNYNSALKTEKRKLTQELSTMKDQLEQLQASSKRQLSRHREQSEKQRR 607
              :..|:. |:|:..|   :.:.|:.|::  |:|..::..|||.....::||:.:.:||:..:.|
Mouse   724 QNVEFLQVIAKREEAI---HQAQLRLEEK--TRECGSLARQLESAIEDARRQVEQTKEQALSKER 783

  Fly   608 DLQKKIYDLELKLSRSQNSTSSLIQERDSLIAELQTQLHTLVHNFEVSQKHIRVLRRHIYSMTNQ 672
            ..|.||.|||.:|||::.....|.:.||......|::|..|....|.|:...|.::.:: .....
Mouse   784 AAQSKILDLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYV-QFLKA 847

  Fly   673 GGTGIVGSGSAGIAHLTS 690
            ....:.|......::|||
Mouse   848 SYANVFGDAPYTSSYLTS 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8851	NP_722917.2	SMC_prok_B	<430..>666	CDD:274008	66/271 (24%)
Odf2	XP_017171761.1	SMC_prok_B	<163..828	CDD:274008	137/685 (20%)