Protein Alignment CG31954 and PROC

DIOPT Version :10

• Sequence 1: NP_722915.1
• Gene: CG31954 / 33572
• FlyBaseID: FBgn0051954
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 99/290 - (34%)
• Similarity: 141/290 - (48%)
• Gaps: 37/290 - (12%)

  Fly     9 LLQCSLLVLAGVCLIP--QPVKRQRSLEDVIKNPWK-LSPRLDGRIVGGHRINITDAPHQVSLQT 70
            ||||...|     ..|  :|.||.......:|...: ...::|.|::.|......|:|.||.|..
Human   267 LLQCHPAV-----KFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLD 326

  Fly    71 SSH--ICGGSIISEEWILTAAHCTYGKTADRLKVRLGTSEFAR--SGQL-LRVQKIVQHAQFNYT 130
            |..  .||..:|...|:||||||.  ..:.:|.||||..:..|  ..:| |.::::..|..::.:
Human   327 SKKKLACGAVLIHPSWVLTAAHCM--DESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKS 389

  Fly   131 NVDYDFSLLQLAHPIKFDETKKAVKLPESQMKYMD----GEACFVSGWGNTQNLLESRE------ 185
            ..|.|.:||.||.|....:|...:.||:|.:...:    |:...|:|||    ...|||
Human   390 TTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWG----YHSSREKEAKRN 450

  Fly   186 ---WLRQVEVPLVNQELCSEKYKQYGGVTERMICAGFLEGGKDACQGDSGGPMVSE---SGELVG 244
               .|..:::|:|....|||.....  |:|.|:|||.|...:|||:||||||||:.   :..|||
Human   451 RTFVLNFIKIPVVPHNECSEVMSNM--VSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVG 513

  Fly   245 VVSWGYGCAKPDYPGVYSRVSFARDWIKEH 274
            :||||.||......|||::||...|||..|
Human   514 LVSWGEGCGLLHNYGVYTKVSRYLDWIHGH 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	86/243 (35%)
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251	2/2 (100%)
		Tryp_SPc	308..543	CDD:238113	86/242 (36%)