Protein Alignment CG31954 and PLAT

DIOPT Version :10

• Sequence 1: NP_722915.1
• Gene: CG31954 / 33572
• FlyBaseID: FBgn0051954
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 88/255 - (34%)
• Similarity: 128/255 - (50%)
• Gaps: 35/255 - (13%)

  Fly    50 RIVGGHRINITDAPHQVSLQTSSH--------ICGGSIISEEWILTAAHCTYGK-TADRLKVRLG 105
            ||.||...:|...|.|.:: .:.|        :|||.:||..|||:||||...: ....|.|.||
Human   310 RIKGGLFADIASHPWQAAI-FAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILG 373

  Fly   106 TSEFARSG---QLLRVQKIVQHAQFNYTNVDYDFSLLQLAHPIKFDETK--------KAVKLPES 159
            .:.....|   |...|:|.:.|.:|:....|.|.:||||    |.|.::        :.|.||.:
Human   374 RTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQL----KSDSSRCAQESSVVRTVCLPPA 434

  Fly   160 QMKYMDGEACFVSGWGNTQNLLE-SREWLRQVEVPLVNQELCSEKYKQYGGVTERMICAGFLEGG 223
            .::..|...|.:||:|..:.|.. ..|.|::..|.|.....|:.::.....||:.|:|||....|
Human   435 DLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSG 499

  Fly   224 ------KDACQGDSGGPMVS-ESGE--LVGVVSWGYGCAKPDYPGVYSRVSFARDWIKEH 274
                  .||||||||||:|. ..|.  |||::|||.||.:.|.||||::|:...|||:::
Human   500 GPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDN 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	87/252 (35%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005
		Tryp_SPc	313..559	CDD:238113	86/250 (34%)