Protein Alignment CG31954 and KLK1

DIOPT Version :10

• Sequence 1: NP_722915.1
• Gene: CG31954 / 33572
• FlyBaseID: FBgn0051954
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 84/252 - (33%)
• Similarity: 124/252 - (49%)
• Gaps: 35/252 - (13%)

  Fly    44 SPRLDGRIVGGHRINITDAPHQVSL-QTSSHICGGSIISEEWILTAAHCTYGKTADRLKVRLGTS 107
            :|.:..|||||........|.|.:| ..|:..|||.::..:|:||||||    .:|..::.||..
Human    18 APPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHC----ISDNYQLWLGRH 78

  Fly   108 EF---ARSGQLLRVQKIVQHAQFNYT---------NVDY--DFSLLQLAHPI-KFDETKKAVKLP 157
            ..   ..:.|.:.|.:...|..||.:         :.||  |..||:|..|. ...:..|.|:||
Human    79 NLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELP 143

  Fly   158 ESQMKYMDGEACFVSGWGNTQNLLESREW-----LRQVEVPLVNQELCSEKYKQYGGVTERMICA 217
            ..:.:.  |..|..||||:    :|...:     |:.|::.::..:.|.:.:.|  .||:.|:|.
Human   144 TEEPEV--GSTCLASGWGS----IEPENFSFPDDLQCVDLKILPNDECKKAHVQ--KVTDFMLCV 200

  Fly   218 GFLEGGKDACQGDSGGPMVSESGELVGVVSWGY-GCAKPDYPGVYSRVSFARDWIKE 273
            |.||||||.|.||||||::.: |.|.||.|||| .|..|:.|.|..||.....||::
Human   201 GHLEGGKDTCVGDSGGPLMCD-GVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIED 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	82/245 (33%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	82/245 (33%)